购物车0
产品总数：61426
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PC54239 | (+)-Cloprostenol isopropyl ester | 157283-66-4 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54250 | (+)-Cloprostenol methyl ester | 56687-85-5 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54233 | (+)-Nutlin-3 | 675576-97-3 | Nutlin-3b 是一种 p53/MDM2 抑制剂，IC50 为 13.6 μM。Nutlin-3b 与 MDM2 的结合活性比 Nutlin-3a 低 150 倍。 |
| PC54232 | (±)-EX-527 | 49843-98-3 | Selisistat (EX-527) 是一种有效和选择性的 SirT1 (黑腹果蝇中的 Sir2) 抑制剂，IC50 值为 123 nM。Selisistat 缓解多种亨廷顿病动物和细胞模型的病理学。 |
| PC54244 | 1-Oleoyl Lysophosphatidic Acid | 65528-98-5 | 1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) 是一种丰富的溶血磷脂酸种类，由于其对 LPA 受体 (LPA receptors) 的强亲和力，具有很高的生物活性。1-Oleoyl lysophosphatidic acid 在大多数实验室中常用作 LPA 受体激活的试剂。1-Oleoyl lysophosphatidic acid 可增加 SRE 驱动的 β-galactosidase 的活性。 |
| PC54245 | 1-Palmitoyl Lysophosphatidic Acid | 7220-34-0 | Product Type|Biochemicals|Lipids|Glycerophospholipids||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia||Research Area|Lipid Biochemistry|Glycerophospholipids |
| PC54236 | 10,13-epoxy-11-methyl-Octadecadienoic Acid | 57818-39-0 | Product Type|Biochemicals|Antioxidants||Product Type|Biochemicals|Lipids|Fatty Acids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs||Research Area|Endocrinology & Metabolism|Metabolic Diseases||Research Area|Lipid Biochemistry|Fatty Acids||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation |
| PC54235 | 16-phenoxy Prostaglandin F2α ethyl amide | 951319-59-8 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54247 | 16-phenoxy tetranor Prostaglandin F2α isopropyl ester | 130209-78-8 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology |
| PC54246 | 16-phenoxy tetranor Prostaglandin F2α methyl ester | 51638-90-5 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology |
| PC54248 | 17-phenyl trinor Prostaglandin F2α methyl ester | 38315-47-8 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology |
| PC54242 | 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide | 1621369-73-0 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology |
| PC54249 | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | 195503-20-9 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology |
| PC54243 | CAY10526 | 938069-71-7 | CAY10526 是特异性的微粒体前列腺素E2合成酶 1 (mPGES1)抑制剂。 CAY10526 通过选择性调节 mPGES1 表达抑制 PGE2 的产生，但不影响 COX-2。CAY10526 在黑色素瘤移植模型中抑制肿瘤生长并增加细胞凋亡。CAY10526 降低 BCL-2 和 BCL-XL (抗凋亡) 蛋白水平并增加 BAX 和 BAK (促凋亡) 以及切割的 caspase 3 水平。CAY10526 在三种表达 mPGES1的黑色素瘤细胞系中抑制细胞活力 (IC50< |
| PC54241 | CAY10561 | 933786-58-4 | Product Type|Biochemicals|Kinase Inhibitors|ERK||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|ERK/MAPK Signaling |
| PC54240 | CAY10570 | 875014-22-5 | Product Type|Biochemicals|Small Molecule Inhibitors|Fatty Acid Metabolism||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids |
| PC54231 | CAY10591 | 839699-72-8 | Product Type|Biochemicals|Small Molecule Activators|Deacetylases||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation||Research Area|Immunology & Inflammation|Innate Immunity |
| PC54230 | CAY10602 | 374922-43-7 | CAY10602 是一种 SIRT1 的激活剂。CAY10602 剂量依赖性地抑制 THP-1 细胞中脂多糖对 NF-κB 的 TNF-α 依赖性诱导。 |
| PC54234 | JTE-907 | 282089-49-0 | JTE-907 是高度选择性，有口服活性的 CB2 受体反向激动剂，在体内表现出抗炎活性。 |
| PC54228 | LY293111 | 161172-51-6 | Etalocib (LY293111) 是具有口服活性的白三烯 (LTB4) 受体的拮抗剂，抑制 [3H]LTB4 结合的Ki 值为 25 nM. Etalocib (LY293111) 抑制LTB4 诱导的钙动员的 lC50 值为 20 nM。Etalocib (LY293111) 可诱导凋亡。 |
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