Prolyl endopeptidase (PREP), also known as prolyl oligopeptidase (POP), a member of the serine protease family, which can specifically hydrolyze the peptide bond of the carboxylterminus of the proline residue in the polypeptide chain, has high activity in the liver. Accumulated evidence suggests that PREP participates in physiological and pathological processes, including maturation and degradation of peptides, inflammation, oxidative stress, autophagy, cell proliferation and cancer.
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PL10087 | BR102910 | 2505339-54-6 | BR102910 是一种选择性的成纤维细胞活化蛋白 (FAP) 抑制剂，IC50 为 2 nM。BR102910 还抑制脯氨酰寡肽酶 (PREP)，IC50 为 49.00 μM。BR102910可用于2型糖尿病的研究。 |
| PL09182 | Prolyl Endopeptidase Inhibitor 1 | 86925-97-5 | Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) 是一种有效的脯氨酸内肽酶 (PEP; PE) 抑制剂，Ki 值为 15 nM。Prolyl endopeptidase-IN-1 具有抗遗忘作用。 |
| PL10086 | S 17092 | 176797-26-5 | S 17092 (S 17092-1) 是一种有效的脑脯氨酰内肽酶 (PEP) 抑制剂，IC50 为 1.2 nM。S 17092 可用于研究与脑衰老相关的记忆障碍和认知障碍。 |
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