Formyl Peptide Receptors

Formyl peptide receptors (FPRs) are a group of G protein-coupled chemoattractant receptors, including FPR1, FPR2 and FPR3. FPR1 and FPR2 are expressed in both monocytes and neutrophils, while FPR3 is found in monocytes but not neutrophils. Besides myeloid cells, FPR1 is expressed in astrocytes, microglial cells, hepatocytes and immature dendritic cells. FPR2 shows an even wider distribution pattern than FPR1 and is expressed in a variety of non-myeloid cells including astrocytoma cells, epithelial cells, hepatocytes, microvascular endothelial cells, neuroblastoma cells, in addition to phagocytic leukocytes. FPRs are classified as Pathogen Recognition Receptors (PRRs) located on immune cells that play a key role in innate immunity due to their ability to recognize both, pathogen associated and damage-associated molecular patterns (PAMPs and DAMPs). FPRs participate not only in host defense and regulation of inflammatory response but also in the migration, proliferation, superoxide production and in several physio-pathological processes due to their unique binding properties and interaction with structurally diverse ligands.

Formyl Peptide Receptors 相关产品（19）

货号	产品名	Cas
PC10939	Ac9-25	284040-76-2
PL02648	ACT-389949	1258417-54-7
PL02914	AG-09/1	356776-32-4
PL03209	BMS-986235	2253947-47-4
PC10971	Boc-MLF	67247-12-5
PL01413	Boc-MLF TFA
PC11040	Cyclosporin H	83602-39-5
PC11284	FPR A14	329691-12-5
PL04904	FPR Agonist 43	903895-98-7
PL01208	HCH6-1	1435265-06-7
PC10959	MMK 1	271246-66-3
PL05904	N-Boc-Phe-Leu-Phe-Leu-Phe	148182-34-7
PC11189	N-Formyl-Met-Leu-Phe	59880-97-6
PL05880	N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys	71901-21-8
PC10860	WKYMVm	187986-17-0
PC10859	WKYMVM	187986-11-4
PL05812	WKYMVM-NH2 TFA	1435781-74-0
PC10894	WRW4	878557-55-2
PL05958	{Boc}-Phe-Leu-Phe-Leu-Phe	66556-73-8