GLUTs (Glucose transporters ) are proteins comprising 12 membrane-spanning regions. GLUTs transport glucose across the plasma membrane by means of a facilitated diffusion mechanism.
GLUT1 (SLC2A1), a uniporter protein, facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. GLUT3 (SLC2A3), mainly present in the brain, has high affinity for glucose. GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT4 (SLC2A4) is found in the heart, skeletal muscle, adipose tissue, and brain. GLUT4 is an insulin-responsive glucose transporter.
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PC12386 | STF 31 | 724741-75-7 | GLUT1和NAMPT抑制剂,STF-31 是一种葡萄糖转运1抑制剂 (GLUT1, IC50 = 1 μM)。 |
| PC12430 | WZB117 | 1223397-11-2 | 葡萄糖转运蛋白1（Glut1）抑制剂,WZB117 是一种葡萄糖转运蛋白 1 (Glut1) 抑制剂，可下调糖酵解，诱导细胞周期停滞，并在体内外抑制癌细胞生长。 |
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