CaMK

The Ca²⁺/calmodulin-dependent kinase (CaMK) family has been recognized as a key mediator in living organisms and various biological processes.

CaMK II is a multifunctional cytoplasmic calcium and calmodulin-dependent protein kinase that phosphorylates and alters the function of a variety of substrates. The CaMK II pathway has been found to regulate the RANKL-induced osteoclast formation via the cAMP-response element binding protein (CREB) pathway.

Among many signaling pathways of proliferation, intracellular calciumol/L has been extensively demonstrated to be very important. In cytoplasm, calciumol/L binds to calmodulin, and then activates the CaMKs which are a family of structurally related serine/threonine protein kinases including CaMKI-IV. CaMKII, a multi functional protein kinase, is ubiquitously involved in many physiological processes including control of cell cycle, apoptosis, gene expression, and neurotransmission.

CaMK 相关产品（12）

货号	产品名	Cas
PL02779	A-3 hydrochloride	78957-85-4
PL05776	Autocamtide 2	129198-88-5
PL05867	Autocamtide 2, amide
PL05775	Autocamtide-2-related inhibitory peptide TFA
PL02351	Cabamiquine succinate	2444781-71-7
PL05857	Calmodulin-Dependent Protein Kinase II(290-309) acetate
PL04791	CaMKII-IN-1	1208123-85-6
PL04439	KN-93 phosphate	1913269-12-1
PL01130	Rimacalib	215174-50-8
PL04952	STO-609	52029-86-4
PL05781	Syntide 2 TFA
PL03695	XST-14	2607143-50-8