ATPases are a class of enzymes that catalyze the decompositionof ATP into ADP and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. Some such enzymes are integral membrane proteins and move solutes across the membrane, typically against their concentration gradient. These are called transmembrane ATPases. Transmembrane ATPases import many of the metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. Such as the sodium-potassium exchanger (or Na+/K+ ATPase) and the hydrogen potassium ATPase (H+/K+ ATPase or gastric proton pump) that acidifies the contents of the stomach.
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PL02091 | ATP synthase inhibitor 1 | 1023043-30-2 | ATP synthase inhibitor 1 是一种 F1/FO-ATP 合酶复合物 c 亚基的有效抑制剂,抑制线粒体通透性转换孔的开放,但不影响 ATP 的水平。 |
| PL04553 | BTB06584 | 219793-45-0 | BTB06584 是一种选择性的且依赖 IF1 的线粒体 F1Fo-ATPase 抑制剂,且不影响 ATP 的合成。BTB06584 可延迟缺血性细胞死亡。 |
扫码关注公众号