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MST1/2

Hippo signaling pathway, also known as the Salvador/Warts/Hippo (SWH) pathway, controls organ size in animals through the regulation of cell proliferationand apoptosis. The Hippo pathway consists of a core kinase cascade in which Hpo phosphorylates the protein kinase Warts (Wts) Hpo (MST1/2 in mammals) is a member of the Ste-20 family of protein kinases. This highly conserved group of serine/threonine kinases regulates several cellular processes, including cell proliferation, apoptosis, and various stress responses.

MST1/2 相关产品(1)
货号 产品名 Cas 产品描述
PC15850 XMU-MP-1 2061980-01-4 MST1/2的强效选择性抑制剂,XMU-MP-1是可逆和选择性的 MST1/2 抑制剂,IC50 分别为71.1和38.1 nM。