购物车0
产品总数：61047
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PC54292 | (-)-Deguelin | 522-17-8 | Deguelin 是一种天然存在的鱼藤酮类化合物，通过阻止多种途径 (如 PI3K-Akt，IKK-NF-κB 和 MAPK-mTOR-survivin 等) 充当化学预防剂。Deguelin 与 Hsp90 的结合导致许多致癌蛋白 (包括 MEK1/2，Akt，HIF1α，COX-2 和 NF-κB) 的表达降低。 |
| PC54282 | 1,2,3-Triheneicosanoyl Glycerol | 26536-14-1 | Product Type|Biochemicals|Lipids|Glycerolipids||Research Area|Lipid Biochemistry|Glycerolipids |
| PC54293 | 17-phenoxy trinor Prostaglandin F2α ethyl amide | 1421369-12-1 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience |
| PC54286 | 17-phenyl trinor Prostaglandin F2α cyclopropyl amide | 1138395-12-6 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology |
| PC54290 | Amiodarone-d4 (hydrochloride) | 1216715-80-8 | Amiodarone-d4 (hydrochloride) 是 Amiodarone hydrochloride 的氘代物。Amiodarone hydrochloride是一种 III 类抗心律失常剂，可抑制野生型IhERG 钾通道及其尾电流，IC50 约为 45 nM。Amiodarone hydrochloride通过成纤维细胞中，Amiodarone hydrochloride ERK1/2 和p38 MAPK 信号传导诱导细胞增殖和肌成纤维细胞分化。Amiodarone hydrochloride可用于室上性和室性心律失常的研究。 |
| PC54291 | Capecitabine-d11 | 1132662-08-8 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Nucleotides/Nucleosides||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cancer|Cell Death||Research Area|Cancer|DNA Damage and Repair||Research Area|Cancer|Metabolism||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Candidiasis |
| PC54289 | Digoxin-d3 | 127299-95-0 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Cardiovascular System|Cardiovascular Diseases|Heart Failure |
| PC54285 | Entacapone-d10 | 1185241-19-3 | Entacapone-d10 是 Entacapone 的氘代物。Entacapone 是一种有效的、可逆的、外周作用和具有口服活性儿茶酚-O-甲基转移酶 (COMT) 抑制剂。Entacapone 对大鼠脑、红细胞和肝脏 COMT 有抑制作用，IC50 值分别为 10 nM、20 nM和160 nM。Entacapone 对 COMT 的选择性优于其他儿茶酚胺代谢酶，包括MAO-A、MAO-B、酚磺基转移酶 M (PST-M) 和 PST-P (IC50s >50 µM)。Entacapone 可用于帕金森病的研究。Entacapone 抑制 FTO 去甲基化活性，IC50 是 3.5 μM，可用于研究代谢紊乱。 |
| PC54283 | HA-1077 (hydrochloride) | 203911-27-7 | Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Kinase Inhibitors|ROCK||Product Type|Biochemicals|Kinase Inhibitors|S6K||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Angiogenesis||Research Area|Cancer|Cell Signaling|ROCK Signaling||Research Area|Cancer|Cell Signaling|S6K Signaling||Research Area|Cardiovascular System|Cardiovascular Diseases|Angina||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Cell Biology|Cell Signaling|ERK/MAPK Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes |
| PC54288 | Ketoconazole-d3 | 1217766-70-5 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Antifungals|Triazoles||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis |
| PC54287 | Oxybutynin-d10 (hydrochloride) | 120092-65-1 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Ophthalmology |
| PC54284 | Risperidone-d4 | 1020719-76-9 | Risperidone-d4 是 Risperidone 的氘代物。Risperidone是 5-HT2 受体的阻断剂，P-糖蛋白 (P-Glycoprotein) 的抑制剂 和 dopamine D2 受体的拮抗剂，其对 5-HT2A 和 dopamine D2 受体的 Ki 值分别为 4.8，5.9 nM。 |
| PC70282 | 氨氯地平杂质11对照品 | 496024-43-2 | |
| PC70283 | 氨氯地平杂质13对照品 | 949155-13-9 | |
| PC70284 | 氨氯地平杂质A对照品 | 88150-62-3 | |
| PC70285 | 氨氯地平杂质B对照品 | 721958-72-1 | |
| PC70286 | 氨氯地平杂质D 盐酸盐对照品 | ||
| PC70287 | 氨氯地平杂质D 盐酸盐对照品（free base） | 113994-41-5 | |
| PC70288 | 氨氯地平杂质F对照品 | 140171-66-0 | |
| PC70289 | 氨氯地平杂质G对照品 | 43067-01-2 |
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