LYTACs PROTAC Linkers PROTACs SNIPERs Target Protein Ligand-Linker Conjugates ATTECs E3 Ligase Ligand-Linker Conjugates Ligands for Target Protein for PROTAC Ligands for E3 Ligase PROTAC-Linker Conjugates for PAC Molecular Glues

Thyroid Hormone Receptor VD/VDR Androgen Receptor Estrogen Receptor/ERR Constitutive Androstane Receptor Glucocorticoid Receptor Nuclear Hormone Receptor 4A/NR4A PPAR LXR Mineralocorticoid Receptor REV-ERB ROR Progesterone Receptor RAR/RXR

Arenavirus Filovirus Enterovirus Flavivirus EBV Dengue virus CMV HIV Protease HIV HCV Protease HCV HBV

Autophagy Atg and Atg-related Protein

Apoptosis Intrinsic Pathway Extrinsic Pathway Ferroptosis Necrotic Cell Death

ADC Linker ADC Cytotoxin Antibody-Drug Conjugates (ADCs) PROTAC-Linker Conjugates for PAC Drug-Linker Conjugates for ADC ADC Antibody

DUB GAK DNA Alkylator/Crosslinker Early 2 Factor (E2F) Haspin Kinase IRE1 Molecular Glues PDI PARG YB-1 Cyclin G-associated Kinase (GAK) Checkpoint Kinase (Chk) ATF6 G-quadruplex DNA/RNA Synthesis Endonuclease DNA Stain ClpP Nucleoside Antimetabolite/Analog Eukaryotic Initiation Factor (eIF) 抗衰老酶 CRISPR/Cas9 极光激酶 P97 ATM/ATR CDK PAK ROCK 去泛素化酶 DNA-PK HDAC HSP PPAR Polo样激酶(PLK) DNA/RNA合成 真核起始因子(eIF) 检查点激酶(Chk) PERK G-四链体 PARP 核苷抗代谢药/类似物 酪蛋白激酶 SRPK 叶酸 Topoisomerase 拓扑异构酶 PAR1 G蛋白偶联受体/G蛋白 c-Myc Rho Cyclin-Dependent Kinases Ksp Haspin PAK4 Cdc7 RAD51 PTEN Wee1 E1 enzyme PAK1 Cdc42 Mitotic Papain DNA Synthesis Telomerase DNA Alkylating Nucleoside Antimetabolite/Analogue DNA Ligases DNA Stains DNA Gel Stain MTH1 tankyrase Modified Nucleotides Cap Products TAK1 PCR Kits

Adenylate Cyclase Amylin Receptor Androgen Receptor Arrestin Bradykinin Receptor CRFR GRK G protein-coupled Bile Acid Receptor 1 GCGR GLP Receptor Glutaminase GPR88 GPR68 GPR52 GPR6 GPR4 GPR139 Macrophage migration inhibitory factor (MIF) MRGPR MCHR1 (GPR24) Mitophagy nAChR NEDD8-activating Enzyme P2Y Receptor 孕激素受体 Serotonin Transporter Succinate Receptor 1 TAAR Adrenergic Receptor 5-HT Receptor Adenosine Receptor Apelin Receptor (APJ) Angiotensin Receptor Cannabinoid Receptor Bombesin Receptor Chemerin Receptor PACAP Receptor CGRP Receptor Taste Receptor Secretin Receptor PTHR RGS Protein ICMT G Protein-coupled Receptor Kinase (GRK) Antiangiogenics OX Receptor RAS Opioid Receptor GPR40 大麻素受体 脂联素受体 5-HT受体 肾上腺素能受体 神经激肽受体 食欲素受体(OX受体) P2Y受体 内皮素受体 血管紧张素受体 mAChR GPR119 胰高血糖素受体 白三烯受体 前列腺素受体 CXCR 组胺受体 褪黑激素受体 PDGFR LPL受体 腺苷受体 CXCR拮抗剂 mGluR LPA Receptor Adenosine Kinase EP1 Receptor GHSR NOP Receptor CaSR Adenosine Deaminase RGS Calcimimetic Agent Vasopressin Receptor ERRγ Glucocorticoid Receptor GPR120 Free Fatty Acid Receptors CCR2 PGD2 Receptor EP4 Receptor GPR109A 17,20-lyase S1P receptor S1P receptor inhibitor GLUT1 NK3 Receptor Oxytocin Receptors Motilin Receptor Sigma Receptor GPR44 CysLT1 receptor Somatostatin Receptor Bombesin Receptors CCK1 Receptors GPCR19 FFAR1（GPR40） PAF Receptors Melatonin Receptors GPR84 Non-selective CRF Apelin Receptor GPR55 Galanin Receptors ETA Receptors NPY Receptors Urotensin-II Receptor CRF1 Receptors NK Receptor NK2 Receptors Protease-Activated Receptors Melanin-concentrating Hormone Receptors Orexin EBI2/GPR183 CCKB Melanocortin (MC) Receptors C3aR Hydroxycarboxylic Acid Receptors CysLT2 receptor Calcitonin and Related Receptors Neurotensin Receptors CCK2 Receptors Acetylcholine Ghrelin Receptors GPR81 Orphan 7-TM Receptors Chemokine Receptors TSH Receptor Peptide Receptors GPR35 Formyl Peptide Receptors GIP Receptor Adrenergic Transporters VIP Receptors ETB Receptors CRF2 Receptors Neuropeptide FF/AF Receptors Gonadotropin-Releasing Hormone Receptors Kisspeptin Receptor Secretin Receptors Neuromedin U Receptors PACAP Receptors Sensory Neuron-Specific Receptors P2X7 receptor

KLF MAP4K MNK MAPKAPK2 (MK2) Mixed Lineage Kinase Ribosomal S6 Kinase (RSK) p38 MAPK JNK RAF 核糖体S6激酶(RSK) MEK ERK MAP3K 混合谱系激酶 p38MAPK MEK1/2 p38 Other MAPK MAPKAPK MKK Protein Kinase G cAMP

ULK DNA-PK ATM/ATR PTEN PIN1 PI4K PIKfyve mTOR PI3K GSK-3 PDK-1 AKT MELK AMPK S6 Kinase CK2 eNOS

MicroRNA TET Protein Epigenetic Reader Domain HuR DNA Methyltransferase Small Interfering RNA (siRNA) SF3B1 Glycosyltransferase Histone Methyltransferase Aurora Kinase METTL3 Histone Demethylase Histone Acetyltransferase Protein Arginine Deiminase Methionine Adenosyltransferase (MAT) 表观遗传读者域 组蛋白甲基转移酶 组蛋白去甲基化酶 DNA甲基转移酶 组蛋白乙酰转移酶 PKC Sirtuin MBT Domains Protein Ser RNA Polymerase Polycomb repressive complex 组蛋白脱甲基酶 SUMOylation PAD Modified Nucleotides (DNA related) High-Fidelity PCR PCR qPCR Reverse Transcription Modified Nucleotides (RNA related) In Vitro Transcription RNA mRNA Superior Choice for Cloning and Genotyping

17β-HSD 11β-HSD 5 alpha Reductase Acetolactate Synthase (ALS) Acetyl-CoA Carboxylase Adenosine Deaminase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Antifolate Arginase COMT CSF & Receptors Deubiquitinase DGK Dihydroorotate Dehydrogenase Epoxide Hydrolase FABP FTO Gutathione S-transferase HPPD Lipoxygenase Liposome LDLR MAT MTHFD MTP Mitochondrial Metabolism Monoamine Oxidase Neprilysin NO Synthase Phosphatase Prolyl Endopeptidase(PREP) Proteasome Pyroptosis RAR/RXR REV-ERB Ser/Thr Protease SHP2 Transketolase TrxR Amylases FBPase FOXO HIF/HIF Prolyl-Hydroxylase Hexokinase Glyoxalase (GLO) Amino Acid/Protein Metabolism Nucleic Acid Metabolism Endogenous Metabolite Glucosidase Acyltransferase 15-PGDH Glutathione Peroxidase ATP Citrate Lyase Ceramidase Adiponectin Receptor Dopamine β-hydroxylase Cathepsin Adenosine Kinase Angiotensin-converting Enzyme (ACE) ADAMTS Aminopeptidase Phosphodiesterase (PDE) Methylenetetrahydrofolate Dehydrogenase (MTHFD) Dihydrofolate reductase (DHFR) HIV Integrase Aminoacyl-tRNA Synthetase Cryptochrome Dipeptidyl Peptidase Drug Metabolite MMP PGC-1α RXR PAI-1 法尼基转移酶 氨肽酶 NAMPT COX 脂肪酸合成酶(FAS) 黄嘌呤氧化酶 凝血酶 艾滋病毒整合酶 GSNOR IDO 磷酸二酯酶(PDE) CETP 蛋白酶体 HIF/HIF脯氨酰-羟化酶 PDHK 弹性蛋白酶 ATGL 组织蛋白酶 盐皮质激素受体 酪氨酸酶 细胞色素P450 SGK Factor Xa 磷酸酶 FXR HIV蛋白酶 E1/E2/E3酶 SCD MAGL 血管紧张素转换酶(ACE) 酰基转移酶 色氨酸羟化酶 多巴胺β-羟化酶 HCV蛋白酶 异柠檬酸脱氢酶(IDH) 二肽基肽酶 Enzyme Tools Dehydrogenase Squalene synthase Folate Analogue DGAT KRAS-PDEδ HLE CPT1 HMG-CoA Reductase Phospholipase Transferase DHFR P450 CYP3A/CYP450 Procollagen C Proteinase Carbonic Anhydrase MAO Neuronal Metabolism Cholesterol absorption monooxygenase C14ɑ demethylase TPH Saccharometabolism Glucokinase Enolase Oxidative Phosphorylation Lipid Metabolism PKM2 Hydrolase 12-Lipoxygenase 其他代谢相关 Amino acid metabolism Galactosidase MGL ornithine decarboxylase Transaminase Pyruvate kinase aldehyde dehydrogenase Renin Synthetases Hydroxylases Endopeptidase 肌醇磷酸酶 Inositol Phosphatases NADPH Oxidase Guanylyl Cyclase Cholinesterases Serine Protease 其他蛋白酶 Calpains HCV Protease NS3/4a protease DPP-4 Carboxypeptidase Urokinase Caspase DUB E2 conjugating E3 Ligase

Ephrin receptor RET Anaplastic lymphoma kinase (ALK) Discoidin Domain Receptor GDNF Receptor BRK JAK SHP2 c-Kit PKA FGFR SYK c-Met/HGFR BTK TAMReceptor SRC ALK DYRK FAK BCR-ABL FLT3 胰岛素受体 c-FMS TrkReceptor VEGF & VEGFR EGFR IGF-1R MEK1/2 TGF-βR1(ALK5) IGF1R HER2 Ack1 EphB4 ITK BMX Kinase IRAK Insulin Receptor Lck LRRK2 ROR PTKs/RTKs Tie-2 Broad Spectrum Protein Kinase Inhibitor Pyk2 Trk DDR1/DDR2 Receptor Axl Tyrosine Kinase

Hippo (MST) Oct3/4 YAP Casein Kinase PKG Organoid GLI Hedgehog Wnt信号 TGF-β/Smad蛋白 Porcupine Notch SMO Smoothened Wnt/β-catenin CK1 EZH2 HSC Cancer stem cell MST1/2 Stem Cell ESC iPSC

EGFR JAK2 PIM JAK STAT interferon receptor

Arenavirus EBV Enterovirus Filovirus FLAP HIV Integrase HPV Huntingtin Influenza Virus Orthopoxvirus RABV TNF Superfamily Virus Protease VSV Beta-lactamase Penicillin-binding protein (PBP) Bacterial Flavivirus Dengue virus Parasite Fungal HIV Protease HCV Protease 细菌 真菌 CMV HCV 寄生物 HIV SARS-CoV抑制剂 Influenza A virus HBV Antibiotic Reverse Transcriptase gp120/CD4 NA RSV HSV Antifungal VEEV

Aquaporin Ion Channel CRAC Channel FATP Ferroportin HCN Channel Na+/H+ Exchanger P2X Receptor Piezo Channel Potassium Channel TOPK VDAC nAChR Apical Sodium-Dependent Bile Acid Transporter ATP Synthase EAAT Monocarboxylate Transporter GLUT GlyT Calmodulin Chloride Channel GABA Receptor P-糖蛋白 单胺转运蛋白 钾通道 GABA受体 氯通道 CRM1 ATP合成酶 钠通道 SGLT URAT1 质子泵 iGluR CFTR 单羧酸转运蛋白 BCRP TRPV1 Calcium Channel ATPase NKCC P2X purinergic receptor NMDA Receptor AMPAR MCT GlyT1 Na+/Ca2+ Exchanger P-gp ICB TRP Channel Cannabinoid Transporters Glutamate (EAAT) Transporters Multidrug Transporters Monoamine transporter Kainate Receptors Chloride Channels Nucleoside Transporters Ionophore Other Channel Modulators Glucose Transporters Glycine Receptors GTPase

Cholecystokinin Receptor Glucosylceramide Synthase Imidazoline Receptor Tau Protein Transthyretin (TTR) α-synuclein AAK1 Calcineurin Amyloid-β Beta-secretase Cholinesterase (ChE) Dopamine Transporter γ-secretase CaMK 疼痛 β-分泌 5-羟色胺转运蛋白 FAAH β淀粉样蛋白

TNF Receptor Survivin 生存素 Bcl-2 Family PKD Ferroptosis IAP MDM-2/p53 RIP激酶 胱天蛋白酶 半胱氨酸蛋白酶 凋亡诱导剂 PC-PLC TNF-α 胸苷酸合酶 Bcl-xL 14.3.3 Proteins Other Apoptosis ASK1 c-RET PAR4 PD-1/PD-L1 APC

Dynamin Gap Junction Protein Arp2/3 Complex Integrin Microtubule/Tubulin Kinesin Myosin 驱动蛋白 肌球蛋白 微管/微管蛋白 MPS1 整合素（Integrin） Arp2/3复合物 动力素

KEAP1-Nrf2 IKK NF-κB MALT1

CD20 CD28 CD22 CD38 CD6 CD73 CD3 Complement System CTLA-4 CX3CR1 Cyclic GMP-AMP Synthase FAP FKBP Galectin IFNAR Mesothelin NOD-like Receptor (NLR) NFAT STING Tim3 BCL6 ALCAM/CD166 AIM2 CD2 CCR CD19 Arginase Aryl Hydrocarbon Receptor CD276/B7-H3 CD74 Toll样受体(TLR) SPHK 血小板生成素受体 (PAFR) 白细胞介素相关 芳基烃受体 其他免疫相关 活性肽 Papain 5-Lipoxygenase IκB/IKK AP-1 PGE synthase PGDS SIKs NOD1 15-lipoxygenase

PKA PKC ROCK TGF-beta/Smad TGF-β Receptor TGF-β受体 SMAD Smad Signaling