购物车0
产品总数：60941
Secreted frizzled-related proteins (SFRPs) are soluble proteins that have highly restricted tissue distribution. SFRPs are capable of binding to Wnts and frizzled (Fz) receptors to interfere with Wnt signaling, which plays a major role in cell fate determination through the regulation of cell proliferation, differentiation, and apoptosis.
sFRP-1 contributes to the inhibition of apoptosis in fibroblast populations. sFRP-1 proteins are involved in apoptosis by negatively modulating wingless/int (WNT) signaling by interacting with either WNTs or Frizzled receptors. By sequestering WNTs, sFRP-1 removes the stimulus for β-catenin stabilization and mediates various biological processes.
SFRP proteins modulate Wnt signalling by interacting with either Wnt or frizzled receptors and are reported to affect epithelial/stromal interactions in prostate cancer.
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PC14807 | WAY 316606 | 915759-45-4 | |
| PC15298 | WAY 316606 HCl(free base) | 915759-45-4 |
Copyright © 2025 陌孚医药 All rights reserved 未经授权禁止拷贝本站所有资料，如有违反，将追究法律责任。
沪ICP备2023012080号 | 
沪公网安备31011402010657号
扫码关注公众号
