AMPK

AMPK (AMP-activated protein kinase) is an enzyme that plays a role in cellular energy homeostasis. It consists of three proteins (subunits) that together make a functional enzyme. The net effect of AMPK activation is stimulation of hepatic fatty acid oxidation andketogenesis, inhibition of cholesterol synthesis, lipogenesis, and triglyceride synthesis, inhibition of adipocyte lipolysis and lipogenesis, stimulation of skeletal muscle fatty acid oxidation and muscle glucose uptake by pancreatic beta-cells. AMPK acts as a metabolic master switch regulating several intracellular systems including the cellular uptake of glucose, the β-oxidation of fatty acids and the biogenesis of glucose transporter 4 (GLUT4) and mitochondria.

AMPK 相关产品（44）

货号	产品名	Cas	产品描述
PC15481	6-[4-(2-哌啶-1-基乙氧基)苯基]-3-吡啶-4-基吡唑并[1,5-A]嘧啶	866405-64-3	AMPK抑制剂，Dorsomorphin 是一种有效的 ATP 竞争性的选择性 AMPK 抑制剂，Ki 为 109±16 nM。
PL05721	7-Methoxyisoflavone	1621-56-3
PC15450	AICAR	2627-69-2	AMPK 激活剂，AICAR是一种可渗透细胞的AMP活化蛋白激酶 (AMPK) 激活剂。
PC15465	AICAR phosphate	681006-28-0
PL04256	Aldometanib
PL05879	AMARA peptide TFA
PC15521	AMPK activator	849727-81-7
PL06134	AMPK activator 1	1152423-98-7
PL03219	AMPK activator 4	2493239-46-4
PL04354	AMPK-IN-3	2417674-27-0
PC15519	Ampkinone	1233082-79-5
PL03601	ASP4132	1640294-30-9
PL01987	BAY-3827	2377576-35-5
PL03415	BC1618	2222094-18-8
PL02611	Bempedoic acid-d4	2408131-70-2
PL02711	COH-SR4	73439-19-7
PC15471	Dorsomorphin 2HCl	1219168-18-9
PL02256	EB-3D	1839150-63-8
PL02101	EX229	1219739-36-2
PC15498	GSK621	1346607-05-3