Ampkinone is an indirect AMP-activated protein kinase (AMPK) activator.
性状
Solid
IC50 & Target[1][2]
AMPK
体外研究(In Vitro)
Ampkinone stimulates the phosphorylation of AMPK via the indirect activation of AMPK in various cell lines. Ampkinone-mediated activation of AMPK requires the activity of LKB1 and results in increased glucose uptake inmuscle cells.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Ampkinone-treated DIO mice significantly reduce total body weight and overall fat mass. Histological examination and measurement of lipid parameters show that Ampkinone effectively improves metabolic abnormalities in the DIO mice model.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.