购物车0
产品总数：60953
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PC54626 | 13,14-dihydro-15-keto-tetranor Prostaglandin D2 | 1204116-69-7 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54627 | 13,14-dihydro-15-keto-tetranor Prostaglandin E2 | 20675-85-8 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54621 | 16(R)-Iloprost | 74843-13-3 | Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54622 | 16(S)-Iloprost | 74843-14-4 | Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54618 | 17(R)-Resolvin D1 | 528583-91-7 | Product Type|Biochemicals|Lipids|Docosanoids||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Fatty Acids||Research Area|Lipid Biochemistry|Lipoxygenase Pathways |
| PC54617 | 1a,1b-dihomo Prostaglandin E1 | 23452-98-4 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Cardiovascular System||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54610 | 2-Methoxyestradiol | 362-07-2 | 2-Methoxyestradiol (2-ME2)，具有口服活性的 17β-雌二醇 (E2) 的内源性代谢产物，是凋亡 (apoptosis) 诱导剂和血管生成 (angiogenesis) 抑制剂，具有有效的抗肿瘤活性。2-Methoxyestradiol 也可破坏微管 (microtubules) 的稳定。2-Methoxyestradiol 是一种有效的超氧化物歧化酶 (SOD) 抑制剂和活性氧生成剂，可诱导转化细胞系 HEK293、癌细胞系 U87 和 HeLa 的自噬 (autophagy)。 |
| PC54615 | Alkynyl-biotin | 1011268-28-2 | Application|Click Chemistry||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area |
| PC54616 | Biotin-azide | 908007-17-0 | Biotin-azide (N-(3-Azidopropyl)biotinamide) 是具有末端叠氮基团的生物素的一种形式。Biotin-azide 用于通过 Click Chemistry 制备各种生物素化的缀合物。 |
| PC54625 | MPI-0441138 | 827030-33-1 | Product Type|Biochemicals||Research Area|Cancer|Cell Death|Apoptosis |
| PC54611 | N-3-oxo-butyryl-L-Homoserine lactone | 148433-27-6 | Product Type|Biochemicals|Homoserine Lactones||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Quorum Sensing||Research Area|Plant Biology |
| PC54612 | N-3-oxo-decanoyl-L-Homoserine lactone | 147795-40-2 | Product Type|Biochemicals|Homoserine Lactones||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing |
| PC54619 | N-3-oxo-hexadecanoyl-L-Homoserine lactone | 925448-37-9 | Product Type|Biochemicals|Homoserine Lactones||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing||Research Area|Plant Biology |
| PC54614 | PD 0325901 | 391210-10-9 | Mirdametinib (PD0325901) 是一种具有口服活性，选择性和非 ATP 竞争性的 MEK 抑制剂，IC50 为 0.33 nM。Mirdametinib 对活化的 MEK1 和 MEK2 的 Kiapp 值为 1 nM。Mirdametinib 抑制 p-ERK1/2 的表达并诱导细胞凋亡 (apoptosis)。Mirdametinib 对多种人类肿瘤异种移植物具有抗癌活性。 |
| PC54609 | Prostaglandin E1 Alcohol | 21562-57-2 | Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54620 | SB 203580 | 152121-47-6 | Adezmapimod (SB 203580) 是一种选择性的，ATP 竞争性的 p38 MAPK 抑制剂，对 SAPK2a/p38 和 SAPK2b/p38β2 的 IC50 分别为 50 nM 和 500 nM。Adezmapimod 抑制 LCK，GSK3β 和 PKBα，IC50 比 SAPK2a/p38 高 100-500 倍。Adezmapimod 不抑制 JNK 活性，是一种自噬 (autophagy) 和线粒体自噬 (mitophagy) 激活剂。 |
| PC54628 | Skyrin | 602-06-2 | Product Type|Biochemicals|Natural Products|Anthraquinones||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cell Biology|Cell Signaling|cAMP Signaling||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism |
| PC54623 | Tenovin-1 | 380315-80-0 | Tenovin-1 是 sirtuin 1 和 sirtuin 2 的抑制剂，同时可激活 p53，具有潜在的癌症研究的潜力。 |
| PC54624 | Tenovin-6 (hydrochloride) | 1011301-29-3 | Tenovin-6 Hydrochloride 是 Tenovin-1 (HY-13423) 的类似物，是一种 p53 转录活性的激活剂。Tenovin-6 Hydrochloride 抑制纯化人 SIRT1、SIRT2 和 SIRT3 蛋白脱乙酰酶活性，IC50 分别为 21 μM、10 μM 和 67 μM。Tenovin-6 Hydrochloride 也能抑制二氢乳清酸脱氢酶 (DHODH)。 |
| PC54613 | Valproic Acid (sodium salt) | 1069-66-5 | Valproic acid (Sodium Valproate) sodium 是一种具有口服活性的 HDAC 抑制剂，IC50 值为 0.5-2 mM，抑制 HDAC1 的活性，(IC50，400 μM)，同时可诱导 HDAC2 的降解。Valproic acid sodium 激活 Notch1 信号并抑制小细胞肺癌 (SCLC) 细胞的增殖。Valproic acid sodium 可用于癫痫、双相情感障碍、代谢疾病、HIV 感染和偏头痛等的研究。 |
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