货号 | 产品名 | Cas | 产品描述 |
---|---|---|---|
PC22042 | diABZI STING Agonist 3 | 2138299-29-1 | diABZI STING agonist 3 is an agonist of stimulator of interferon genes (STING).1 It binds to STING (IC50 = 0.32 nM in a FRET assay) and induces STING transcriptional activity in a reporter assay (EC50 = 31.62 nM). diABZI STING agonist 3 increases protein levels of Nod-like receptor protein 3 (NLRP3), IL-1β, and IL-18, but not cGAS or mtDNA, in macrophages. |
PC22002 | MD2-TLR4-IN-1. | 2249801-12-3 | MD2-TLR4-IN-1 (Compound 22m) 是一种 myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) 的有效抑制剂。 |
PC22044 | Thunbergol | 25269-17-4 | Thunbergol (Isocembrol) (Compound 17) 是TNF-α的有效抑制剂 (IC 50 = 7.2 μM)。 |