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产品总数：61053
| 货号 | 产品名 | Cas | 产品描述 |
|---|---|---|---|
| PC54178 | Gabapentin | 60142-96-3 | Gabapentin 是一种口服有效的 P/Q 型 Ca<sup>2+</sup> 通道阻滞剂。Gabapentin 抑制神经元 Ca<sup>2+</sup> 内流和减少神经递质释放。Gabapentin 是 GABA 类似物，可用于缓解神经性疼痛。 |
| PC54195 | GW 9508 | 885101-89-3 | GW9508 是一种有效的选择性 G 蛋白偶联受体 FFA1 (GPR40) 和 GPR120 激动剂，pEC50 值分别为 7.32 和 5.46。GW9508 对 GPR40 的选择性是 GPR120 的 100 倍左右，对其他 GPCR，激酶，蛋白酶，整联蛋白和 PPAR 无活性。GW9508 是一种葡萄糖敏感性胰岛素促分泌剂和 ATP 敏感性钾 (KATP) 通道开放剂。GW9508 具有抗炎和抗动脉粥样硬化活性。 |
| PC54217 | L-759,633 | 174627-50-0 | Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors |
| PC54186 | Leelamine (hydrochloride) | 16496-99-4 | Leelamine hydrochloride 是一种从松树皮中提取的三环二萜分子。Leelamine hydrochloride 是一种大麻素 1 型 (CB1) 激动剂，也是前列腺癌细胞中 SREBP1 调节的脂肪酸/脂质合成的抑制剂，不受雄激素受体状态的影响。Leelamine hydrochloride 抑制调节脂肪酸合成的雄激素受体 (androgen receptor) 的转录活性。 |
| PC54160 | Leukotriene E4-d5 | 1240398-14-4 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Leukotrienes||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Lipid Biochemistry|Lipoxygenase Pathways |
| PC54162 | N-butyryl-L-Homoserine lactone | 67605-85-0 | N-Butanoyl-L-homoserine lactone (C4-HSL) 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。N-Butanoyl-L-homoserine lactone 具有抗菌活性，可用于抗菌生物膜。N-Butanoyl-L-homoserine lactone 适配体可用于阻止群体感应和抑制铜绿假单胞菌 (<i>Pseudomonas aeruginosa</i>) 生物膜的形成。 |
| PC54163 | N-butyryl-L-Homoserine lactone-d5 | 2701379-46-4 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Homoserine Lactones||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing |
| PC54161 | N-hexanoyl-L-Homoserine lactone-d3 | 2705226-73-7 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Homoserine Lactones||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Quorum Sensing |
| PC54210 | O-2545 (hydrochloride) | 874745-43-4 | Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors |
| PC54155 | Oleoyl Ethanolamide-d2 | 1245477-09-1 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Fatty Amides||Product Type|Biochemicals|Lipids|Octadecanoids||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids |
| PC54168 | OSU03012 | 742112-33-0 | Product Type|Biochemicals|Lipids|Fatty Acids||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Glycerophospholipids|Phosphatidyl Inositol Kinases & Phosphatases |
| PC54156 | Palmitoyl Ethanolamide-d4 | 1159908-45-8 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Fatty Amides||Research Area|Immunology & Inflammation|Allergy||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids |
| PC54170 | Perifosine | 157716-52-4 | Perifosine是一种有口服活性的 Akt 抑制剂，抑制不同肿瘤细胞系增殖的 IC50 值为0.6-8.9 μM。 |
| PC54212 | PI-103 | 371935-74-9 | PI-103 是一种有效的 PI3K 和 mTOR 抑制剂，抑制 p110α，p110β，p110δ，p110γ，mTORC1 和 mTORC2，IC50 分别为 8 nM，88 nM，48 nM，150 nM，20 nM 和 83 nM。PI-103 还抑制 DNA-PK，IC50 为 2 nM。PI-103 诱导自噬 (autophagy)。 |
| PC54213 | PIK-93 | 593960-11-3 | PIK-93 是一种合成的，有效的 PI4KIIIβ 抑制剂，IC50 值为 19 nM，同时可抑制 PI3Kγ和 PI3Kα 的活性，IC50 值分别为 16 nM 和 39 nM。 |
| PC54180 | Prostaglandin D2 methyl ester | 49852-81-5 | Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypotension||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54189 | Prostaglandin F1α-d9 | 1542166-81-3 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway |
| PC54171 | PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) | 1628353-01-4 | Product Type|Biochemicals|Lipids|Glycerophospholipids||Product Type|Biochemicals|Phosphoinositides|Phosphatidylinositols||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Cell Biology|Inositol Phosphates||Research Area|Lipid Biochemistry|Glycerophospholipids |
| PC54158 | Resolvin E1 | 552830-51-0 | Product Type|Biochemicals|Lipids|Lipoxins/Resolvin Es||Research Area|Immunology & Inflammation|Gastric Disease|Ulcerative Colitis||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways||Research Area|Lipid Biochemistry|Lipoxygenase Pathways |
| PC54172 | Sphingosine-1-phosphate-d7 (d18:1) | 2260670-15-1 | Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Sphingolipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience|Neuroprotection |
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