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Olopatadine-d3 (hydrochloride)

(Synonyms: 盐酸奥洛他定 d

目录号: PL14934

Olopatadine-d3 (hydrochloride) 是 Olopatadine hydrochloride 的氘代物。Olopatadine 盐酸盐(ALO4943A) 是组胺受体阻断剂，可作用于过敏性结膜炎。

CAS No. :1331635-21-2

商品编号	规格	价格	会员价	是否有货	数量
PL14934-1mg	1mg	询价	询价
PL14934-10mg	10mg	询价	询价

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中文名称	Olopatadine-d3 (hydrochloride)
中文别名	[2H3]-奥洛他定盐酸盐;奥洛他定杂质26
英文名称	Olopatadine-d3 (hydrochloride)
英文别名	Olopatadine-d3 Hydrochloride;HVRLZEKDTUEKQH-NEGCSKJWSA-N;[2H3]- Olopatadine Hydrochloride
Cas No.	1331635-21-2
分子式	C₂₁H₂₄ClNO₃
分子量	376.89
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.
详情描述	Olopatadine-d3 (hydrochloride) 是 Olopatadine hydrochloride 的氘代物。Olopatadine 盐酸盐(ALO4943A) 是组胺受体阻断剂，可作用于过敏性结膜炎。

产品详情	Olopatadine-d₃ (hydrochloride) 是 Olopatadine hydrochloride 的氘代物。Olopatadine 盐酸盐(ALO4943A) 是组胺受体阻断剂，可作用于过敏性结膜炎。
生物活性	Olopatadine-d 3 (hydrochloride) (ALO4943A-d3) is the deuterium labeled Olopatadine hydrochloride. Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis[1][2].
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tamura, T., et al., Effect of olopatadine and other histamine H1 receptor antagonists on the skin inflammation induced by repeated topical application of oxazolone in mice. Pharmacology, 2005. 75(1): p. 45-52.

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[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Tamura, T., et al., Effect of olopatadine and other histamine H1 receptor antagonists on the skin inflammation induced by repeated topical application of oxazolone in mice. Pharmacology, 2005. 75(1): p. 45-52.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Olopatadine-d3 (hydrochloride)

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