N-Acetyl-D-cysteine

目录号: PL10941 纯度: ≥97.0%
N-Acetyl-D-cysteine 具有抗氧化活性,通过与巯基反应清除 ROS,但不能进入谷胱甘肽代谢途径。
CAS No. :26117-28-2
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中文名称
N-Acetyl-D-cysteine
中文别名
N-乙酰基-D-半胱氨酸
英文名称
N-Acetyl-D-cysteine
英文别名
D-Cysteine, N-acetyl-;(2S)-2-acetamido-3-sulfanylpropanoic acid;N-ACETYL-D-CYSTEINE;acetylcysteine;D-Cysteine,N-acetyl;Lopac-A-7250;N-acetyl-3-mercaptoalanine;N-Acetylcysteine;N-Acetyl-D-cysteine
Cas No.
26117-28-2
分子式
C5H9NO3S
分子量
163.19
包装储存
4°C, stored under nitrogen In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
详情描述

N-Acetyl-D-cysteine 具有抗氧化活性,通过与巯基反应清除 ROS,但不能进入谷胱甘肽代谢途径。

产品详情
N-Acetyl-D-cysteine 具有抗氧化活性,通过与巯基反应清除 ROS,但不能进入谷胱甘肽代谢途径。
生物活性
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway.
性状
Solid
体外研究(In Vitro)
N-Acetyl-D-cysteine (20 mM; 1 hour pretreatment; 12 hours) does not increase intracellular GSH levels, but GSH monoester does. D-NAC can not enhance hypoxic apoptosis. This demonstrate that GSH rather than D-NAC or NAC is responsible for enhancing hypoxic apoptosis.
has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, stored under nitrogen In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
参考文献
[1]. Maika Deffieu, et al. Glutathione Participates in the Regulation of Mitophagy in Yeast.J Biol Chem. 2009 May 29;284(22):14828-37.
[2]. B K Wong,et al. Selective Effects of N-acetylcysteine Stereoisomers on Hepatic Glutathione and Plasma Sulfate in Mice. Toxicol Appl Pharmacol
[3]. Suparna Qanungo, et al. N-Acet
溶解度数据
In Vitro: H2O : 250 mg/mL (1531.96 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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