您当前的位置：

Uric acid sodium

(Synonyms: 尿酸钠; Monosodium urate)

目录号: PL10929 纯度: ≥99%

Uric acid sodium (Monosodium urate) 是氧自由基 (oxygen radical) 的清除剂，是一种非常重要的抗氧化剂，有助于维持血压的稳定和抗氧化应激。Uric acid sodium 能清除活性氧 (ROS)，如单线态氧和过氧亚硝酸盐，抑制脂质过氧化。

CAS No. :1198-77-2

商品编号	规格	价格	会员价
PL10929-200mg	200mg	¥803.00	请登录
PL10929-500mg	500mg	询价	询价
PL10929-1g	1g	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

*注意事项:下单时请联系销售核实产品价格及货期，避免后续产生不便，感谢支持!

加入购物车在线咨询收藏产品大包装询价

中文名称	Uric acid sodium
中文别名	尿酸二氢钠;尿酸钠;杀那特;尿酸钠盐;2,6,8-三羟基嘌呤;尿酸钠盐
英文名称	Uric acid sodium
英文别名	1H-Purine-2,6,8(3H)-trione,7,9-dihydro-, sodium salt (1:1);Uric Acid (sodium salt);URIC ACID SODIUM SALT;Harnsaeure,Natrium-Salz;MONOSODIUM URATE;SODIUM ACID URATE;SODIUM ACID URATE SODIUM SALT;SODIUM URATE;uric;Uric acid monosodium;URIC ACID MONOSODIUM SALT;uric acid,sodium-salt;uricacidsodium;Sodium 2,6,8-trioxo-1,2,6,7,8,9-hexahydropurin-3-ide;Uric acid, monosodium salt;7,9-Dihydro-1H-purine-2,6,8(3H)-trione, monosodium salt;1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-, monosodium salt;DSSTox_CID_26828;DSSTox_RID_81940;DSSTox_GSID_46828;WA4Q622EWK;1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-, sodium salt (1:1);NAFSTSRULRIERK-UHFFFAOYSA-M;Tox21_112696;Tox21_112696_1;Uric acid sodium;Sodium acid urate
Cas No.	1198-77-2
分子式	C₅H₃N₄NaO₃
分子量	190.09
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述	Uric acid sodium (Monosodium urate) 是氧自由基 (oxygen radical) 的清除剂，是一种非常重要的抗氧化剂，有助于维持血压的稳定和抗氧化应激。Uric acid sodium 能清除活性氧 (ROS)，如单线态氧和过氧亚硝酸盐，抑制脂质过氧化。

产品详情

生物活性

Uric acid sodium (Monosodium urate), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.

性状

Solid

IC50 & Target[1][2]

Human Endogenous Metabolite

体外研究(In Vitro)

Uric acid (400 μM; 48 hours) sodium protects Caco-2 cells from indomethacin-induced lipid peroxidation.
Co-treatment of cells with Indomethacin and Uric acid (200 μM IND plus 400 μM UA; 24 hours) sodium significantly decreases ROS levels compared to those in cells incubated with indomethacin alone. Cell viability in Caco-2 cells treated with both Indomethacin and Uric acid (200 μM IND plus 400 μM UA; 24 hours) sodium is higher than that in cells treated with indomethacin alone. Uric acid sodium has a protective effect on indomethacin-induced intestinal cell changes through its antioxidant activity. has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

Uric acid (250 mg/kg; p.o.) sodium ameliorates indomethacin-induced enteropathy.
Oral administration of uric acid sodium decreases ROS accumulation in the ileum in a mouse model of indomethacin-induced enteropathy. has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

ClinicalTrial

参考文献

[1]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017;32(11):1839-1845.
[2]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50(4):359-375.

溶解度数据	In Vitro: DMSO : 3.12 mg/mL (16.41 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Uric acid sodium

相关产品

The molarity calculator equation

The dilution calculator equation