HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical.
性状
Solid
体外研究(In Vitro)
HKSOX-1r (5/6-mixture) (2 μM; 30 min) detects mitochondrial respiratory inhibitor-induced O2 formation in a highly sensitive and rapid manner in HCT116, BV-2 and RAW264.7 cells. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
HKSOX-1r (5/6-mixture) (10 μM; 20 min) detects distinct fluorescence distribution in zebrafish embryos are subjected to challenge of PMA or Antimycin A. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Hu JJ, et, al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc. 2015 Jun 3;137(21):6837-43.
溶解度数据
In Vitro: DMSO : 20 mg/mL (23.38 mM; Need ultrasonic)配制储备液