Tromantadine hydrochloride|41544-24-5|(盐酸曲金刚胺)-陌孚医药/Medlife

您当前的位置：

Tromantadine hydrochloride (Synonyms: 盐酸曲金刚胺)

目录号: PL06118 纯度: ≥98%

CAS No. :41544-24-5

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Tromantadine hydrochloride
中文别名	曲金刚胺盐酸盐
英文名称	Tromantadine hydrochloride
英文别名	N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide,hydrochloride;Tromantadine hydrochloride;Tromantadine (hydrochloride);H09LUS437B;Virumerz;Viruserol;Viru-merz;Tromantadine HCl;Tromantadin hydrochlorid;Viru-Merz (TN);D08652;Q27279404;N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide;hydrochloride
Cas No.	41544-24-5
分子式	C₁₆H₂₉ClN₂O₂
分子量	316.87
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情	Tromantadine hydrochloride，Amantadine 衍生物，具有抗疱疹活性，可抑制单纯疱疹病毒1型 (HSV-1) 和 HSV-2 的复制。
生物活性	Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication.
性状	Solid
IC50 & Target[1][2]	HSV-1 HSV-2
体外研究(In Vitro)	Treatment of the cells with 10 to 50μg of Tromantadine reduces HSV-induced cytopathic effect. Treatment with 100 to 500μg of Tromantadine inhibits herpes simplex virus-induced cytopathic effect and reduces virus production. Complete inhibition of virus production is observed with treatments of 500μg to 1 mg. The antiherpetic activity of Tromantadine is dependent upon the viral inoculum size and the time of addition of the compound with respect to infection. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Rosenthal KS, et al. Tromantadine: inhibitor of early and late events in herpes simplex virus replication. Antimicrob Agents Chemother. 1982 Dec;22(6):1031-6.

溶解度数据	In Vitro: DMSO : 62.5 mg/mL (197.24 mM; Need ultrasonic)配制储备液

搜索质检报告(COA)

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品