Valacyclovir-d4, Hydrochloride;ZCDDBUOENGJMLV-SRNSESIXSA-N;[2H4]-Valacyclovir, Hydrochloride;Valacyclovir D4 HydrochlorideQ: What is
Valacyclovir D4 Hydrochloride Q: What is the CAS Number of
Valacyclovir D4 Hydrochloride Q: What is the storage condition of
Valacyclovir D4 Hydrochloride Q: What are the applications of
Valacyclovir D4 Hydrochloride;Valacyclovir-d4 (hydrochloride)
Cas No.
1331910-75-8
分子式
C13H21ClN6O4
分子量
364.82
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
Valacyclovir-d 4 (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral drug for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a prodrug of Aciclovir (HY-17422)[1][2][3][4][5].
体外研究(In Vitro)
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.[2]. Valacyclovir. New indication: for genital herpes, simpler administration. Can Fam Physician. 1999 Jul;45:1698-700, 1703-5.[3]. Lycke J, et al. Acyclovir levels in serum and