β-Amyloid (1-40) (rat)|144409-98-3|(β淀粉样肽(1-40)(鼠))-陌孚医药/Medlife

您当前的位置：

β-Amyloid (1-40) (rat) (Synonyms: β淀粉样肽(1-40)(鼠))

目录号: PL05843 纯度: ≥95%

CAS No. :144409-98-3

商品编号	规格	价格	会员价
PL05843-1mg	1mg	¥3536.00	请登录
PL05843-5mg	5mg	询价	询价
PL05843-10mg	10mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	β-Amyloid (1-40) (rat)
中文别名	BETA-淀粉样肽(1-40);beta-淀粉样肽(1-40)
英文名称	β-Amyloid (1-40) (rat)
英文别名	Amyloid-beta Protein (1-40), mouse, rat;Amyloid β-peptide (1-40) (rat);R at aMyloid-beta peptide 1-40;Rat aMyloid-β peptide 1-40;H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH;Amyloid beta-peptide (1-40) (rat);Amyloid β -Protein (1-40) (mouse, rat);Amyloidβ-Protein(1-40)(mouse00rat);DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVV;CID 131954565;Amyloid β-peptide (1-40) rat;Amyloid ;Amyloid beta-peptide (1-40) rat
Cas No.	144409-98-3
分子式	C₁₉₀H₂₉₁N₅₁O₅₇S
分子量	4233.72
包装储存	Sealed storage, away from moisture and lightPowder -80°C 2 years；-20°C 1 year

产品详情	β-Amyloid (1-40) (rat) 是一种大鼠形式的淀粉样 β-肽，它作为不溶性细胞外沉积物积聚在神经元周围，引起与阿尔茨海默病 (AD) 相关的老年斑。β-Amyloid (1-40) (rat) 增加 ⁴⁵Ca²⁺ 内流，诱导大鼠海马 CA1 亚区神经元变性。β-Amyloid (1-40) (rat) 诱导细胞凋亡 (apoptosis)。 β-Amyloid (1-40) (rat) 可以用于阿尔茨海默病的研究。
生物活性	β-Amyloid (1-40) (rat) is a rat form of the amyloid β-peptide, which accumulates as an insoluble extracellular deposit around neurons, giving rise to the senile plaques associated with Alzheimers disease (AD). β-Amyloid (1-40) (rat) increases Ca influx, induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield. β-Amyloid (1-40) (rat) induces apoptosis. β-Amyloid (1-40) (rat) can be used for the research of Alzheimers disease.
性状	Solid
体外研究(In Vitro)	β-Amyloid (1-40) (rat) (1 μM; 1 h) increases Ca influx and elevates Ca in cortical synaptosomes. β-Amyloid (1-40) (rat) (3 nM) induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield and induces apoptosis. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	β-Amyloid (1-40) (rat) (1.7 mg; ICV, for 7 d; swiss and C57BL/6 mice) induces the learning and memory deficits in mice. has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Swiss and C57BL
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisture and lightPowder -80°C 2 years；-20°C 1 year
SequenceShortening	DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVV
Sequence	Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Solvent&Solubility	In Vitro: H₂O Peptide Solubility and Storage Guidelines:1. Calculate the length of the peptide.2. Calculate the overall charge of the entire peptide according to the following table:
参考文献	[1]. MacManus A, et, al. Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-1beta. J Biol Chem [2]. Miguel-Hidalgo JJ, et, al. Beta-amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Acta Neuropathol. 1998 May;95(5):455-65.

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation