Buspirone hydrochloride 是一种5-HT1A受体激动剂 (5-HT1A receptor)。Buspirone hydrochloride 可用于焦虑和抑郁研究。

Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research.

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Buspirone hydrochloride (0-400 μg/mL; 6 hours) has cytotoxic effect in Lymphocytes.Buspirone hydrochloride (0-180 μg/mL; 0-3 hours; Lymphocytes) induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG). has not independently confirmed the accuracy of these methods. They are for reference only.Cell Viability Assay Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) reduces anxiety/depression behaviors.
Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota. has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
ClinicalTrial
参考文献	[1]. Salimi A, et, al. Analysis of Toxicity Effects of Buspirone, Cetirizine and Olanzapine on Human Blood Lymphocytes: in Vitro Model. Curr Clin Pharmacol. 2018;13(2):120-127. [2]. Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11(1):6094.