Bambuterol hydrochloride|81732-46-9|(盐酸班布特罗; (±)-Bambuterol hydrochloride; KWD-2183 hydrochloride)-陌孚医药/Medlife

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Bambuterol hydrochloride (Synonyms: 盐酸班布特罗; (±)-Bambuterol hydrochloride; KWD-2183 hydrochloride)

目录号: PL14267 纯度: ≥99%

Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) 是肾上腺素受体长效激动剂，Terbutaline的前体药物。

CAS No. :81732-46-9

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中文名称	Bambuterol hydrochloride
中文别名	盐酸班部特罗;1-[双-(3',5'-N,N-二甲氨甲酰氧基)苯基]-2-N-叔丁基氨基乙醇盐酸盐;班布特罗盐酸盐;盐酸班布特罗;Bambuterol Hydrochloride 班布特罗盐酸盐;WITEGABA031盐酸班布特罗标准品;班布特罗盐酸盐标准品;科研实验盐酸班布特罗;临床实验盐酸班布特罗;盐酸氨溴素;盐酸班布特罗 EP标准品;盐酸班布特罗标准品;盐酸班布特罗粉末;盐酸班布特罗固体状;盐酸班布特罗中间体;盐酸班部特罗(盐酸班布特罗);盐酸班部特罗杂质;医药级盐酸班布特罗;班布特罗盐酸盐,10mg 标准品
英文名称	Bambuterol hydrochloride
英文别名	Bambuterol hydrochloride;Dimethylcarbamic acid 5-[2[(1,1-dimethyl)amino]1-hydroxyethyl]-1,3-phenylene ester hydrochloride;[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate,hydrochloride;(¡À)-Bambuterol hydrochlorid;(±)-Bambuterol hydrochloride;KWD-2183;Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester;Bambuterol HCl;Bambuterol (hydrochloride);DSSTox_RID_80925;DSSTox_CID_25515;DSSTox_GSID_45515;Prestwick_777;Bambuterolhydrochloride;bambuterol-hci;[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate;hydrochloride;Bambec (TN);MLS002153784;C18H30ClN3O5;SPECTRUM15;KWD-2183 hydrochloride
Cas No.	81732-46-9
分子式	C₁₈H₃₀ClN₃O₅
分子量	403.90
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情

Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) 是肾上腺素受体长效激动剂，Terbutaline的前体药物。

生物活性

Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.

性状

Solid

IC50 & Target[1][2]

beta-adrenoceptor

体外研究(In Vitro)

Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor. has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

ClinicalTrial

参考文献

[1]. Bambuterol, From Wikipedia

溶解度数据	In Vitro: DMSO : 120 mg/mL (297.10 mM; Need ultrasonic)H₂O : 2.4 mg/mL (5.94 mM; Need ultrasonic)配制储备液

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产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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