Osteogenic Growth Peptide (10-14)|105250-85-9|(OGP(10-14); Historphin)-陌孚医药/Medlife

您当前的位置：

Osteogenic Growth Peptide (10-14) (Synonyms: OGP(10-14); Historphin)

目录号: PL11424 纯度: ≥99%

CAS No. :105250-85-9

商品编号	规格	价格	会员价
PL11424-1mg	1mg	¥4018.00	请登录
PL11424-5mg	5mg	¥10125.00	请登录
PL11424-10mg	10mg	¥16876.00	请登录
PL11424-50mg	50mg	询价	询价
PL11424-100mg	100mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Osteogenic Growth Peptide (10-14)
英文名称	Osteogenic Growth Peptide (10-14)
英文别名	Glycine,L-tyrosylglycyl-L-phenylalanylglycyl-;OSTEOGENIC GROWTH PEPTIDE (10-14);Osteogenic Growth Peptide (10-14), OGP (10-14);Glycine,N-(N-(N-(N-L-tyrosylglycyl)-L-phenylalanyl)glycyl);historphin;H-TYR-GLY-PHE-GLY-GLY-OH;OGP (10-14);Tyr-Gly-Phe-Gly-gly;Tyrosyl-glycyl-phenylalanyl-glycyl-glycine
Cas No.	105250-85-9
分子式	C₂₄H₂₉N₅O₇
分子量	499.52
包装储存	Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years；-20°C 1 ye

产品详情	Osteogenic Growth Peptide (10-14) (OGP(10-14)), 是成骨生长肽 (OGP) C 端截短的五肽，保留了完整的 OGP 样活性。Osteogenic Growth Peptide (10-14) 与 OGP 受体结合并激活细胞内 Gi 蛋白激酶信号通路。Osteogenic Growth Peptide (10-14) 是一种有效的有丝分裂原和促成骨和造血因子。Osteogenic Growth Peptide (10-14) 是 Src 抑制剂。
生物活性	Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP), retains the full OGP-like activity. Osteogenic Growth Peptide (10-14) is responsible for the binding to the OGP receptor and activates an intracellular Gi-protein-MAP kinase signaling pathway. Osteogenic Growth Peptide (10-14) is a potent mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acts as a Src inhibitor.
性状	Solid
体外研究(In Vitro)	Osteogenic Growth Peptide (10-14) (OGP(10-14)) induces proliferation and differentiation in fibroblast and osteoblast cell lines. Osteogenic Growth Peptide (10-14) induces TPO-primed M07-e cells differentiation through RhoA/TGFβ1/SFKs signalling pathway. In particular Historphin acts as a Src inhibitor, showing the same effects of PP2. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Osteogenic Growth Peptide (10-14) (OGP(10-14)) increases bone formation and trabecular bone density and stimulates fracture healing when administered to mice and rats. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years；-20°C 1 ye
SequenceShortening	YGFGG
参考文献	[1]. Chen YC, et al. Bioactive pseudopeptidic analogues and cyclostereoisomers of osteogenic growth peptide C-terminal pentapeptide, OGP(10-14). J Med Chem. 2002;45(8):1624-1632. [2]. Chen Z, et al. Regulation of endochondral ossification by osteogenic growth peptide C-terminal pentapeptide [OGP(10-14)]. Protein Pept Lett. 2009;16(9):1074-1080.

溶解度数据	In Vitro: DMSO : 8.93 mg/mL (17.88 mM; ultrasonic and warming and heat to 60°C)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation