KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL).
性状
Solid
体内研究(In Vivo)
KX1-004 (30 μM) provides significant protection against noise-induced temporary threshold shift (TTS), permanent threshold shift (PTS) and outer hair cells (OHC) loss.
KX1-004 (50 mg/kg) is effective against noise exposure.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.