Carboprost tromethamine|58551-69-2|-陌孚医药/Medlife

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Carboprost tromethamine

目录号: PL10104 纯度: ≥98%

CAS No. :58551-69-2

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中文名称	Carboprost tromethamine
中文别名	卡前列素氨基丁三醇;(Z)-7-[(3R,5S)-3,5-二羟基-2-[(E,3S)-3-羟基-3-甲基辛-1-烯基]环戊基]庚-5-烯酸氨基丁三醇;2-甲氧基-4-氨基-5-乙硫基苯甲酸;卡波前列素氨基丁三醇 EP标准品;卡前列素;卡前列素氨丁三醇;卡前列素氨丁三醇 USP标准品;卡前列素氨丁三醇标准品;卡前列素丁三醇;卡前列腺素;卡前列腺氨丁三醇;前列素氨基丁三醇
英文名称	Carboprost tromethamine
英文别名	Carboprost tromethamine;(Z)-7-[(1R,2S,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-3-methyl-oct-1-enyl]cyclopentyl]hept-5-enoic acid 2-amino-2-(hydroxymethyl)propane-1,3-diol;Carboprost Tromethanimine;CARBOPROST TROMETAMOL;Carboprost
Cas No.	58551-69-2
分子式	C₂₁H₃₆O₅^.C₄H₁₁NO₃
分子量	489.64
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情	Carboprost tromethamine 是前列腺素 F_2α (prostaglandin F2α) 的 15 甲基类似物。Carboprost tromethamine 能有效促进子宫规律性收缩，显著减少产后出血量。
生物活性	Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F 2α . Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery.
性状	Solid
体内研究(In Vivo)	Carboprost tromethamine has a significant effect on the prevention of postpartum hemorrhage in cesarean section, and has a significant effect on improving the state of hypercoagulable blood and maintaining the stable hemodynamic state. Carboprost tromethamine has been accounted for to be 84-96% successful in the treatment of persistent hemorrhage because of uterine atony. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Ling Z, et al. Effect of carboprost tromethamine in prevention of postpartum hemorrhage in cesarean section. Pak J Pharm Sci. 2018 Sep;31(5(Special)):2257-2262. [2]. Bai J, et al. A comparison of oxytocin and carboprost tromethamine in the prevention of postpartum hemorrhage in high-risk patients undergoing cesarean delivery. Exp Ther Med. 2014 Jan;7(1):46-50. Epub 2013 Nov 1.

溶解度数据	In Vitro: H₂O : 125 mg/mL (255.29 mM; Need ultrasonic)DMSO : 100 mg/mL (204.23 mM; Need ultrasonic)配制储备液

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