LL-37, human acetate||-陌孚医药/Medlife

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LL-37, human acetate

目录号: PL13860 纯度: ≥99%

商品编号	规格	价格	会员价
PL13860-1mg	1mg	¥2009.00	请登录
PL13860-5mg	5mg	¥4178.00	请登录
PL13860-10mg	10mg	询价	询价
PL13860-50mg	50mg	询价	询价

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中文名称	LL-37, human acetate
英文名称	LL-37, human acetate
包装储存	Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years；-20°C 1 ye

产品详情	LL-37, human acetate 是一种具有 37 个残基的两亲性组织蛋白酶衍生的抗菌肽，具有广泛的抗菌活性。LL-37, human acetate 有助于保护角膜免受感染，调节伤口愈合。
生物活性	LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing.
性状	Solid
体外研究(In Vitro)	LL-37, human acetate (1-20 μg/mL; 24 h) affects HCECs migration. LL-37, human acetate (0.0001-5 μg/mL;6-24 h) affects cytokine secretion in HCECs. LL-37, human acetate (1-100 μg/mL; 24 h) shows dose-dependently cytotoxic to HCECs at concentrations over 10 μg/mL. has not independently confirmed the accuracy of these methods. They are for reference only.Cell Migration Assay
体内研究(In Vivo)	LL-37, human acetate (0.4-2.0 mg/kg; intratracheal injection once) ameliorates MRSA-induced pneumonia of mice. has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: 6-8 week-old C57BL/6 mic
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years；-20°C 1 ye
SequenceShortening	LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
参考文献	[1]. Dürr UH, et al. LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta. 2006 Sep;1758(9):1408-25. [2]. Huang LC, et al. Multifunctional roles of human cathelicidin (LL-37) at the ocular surface. Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2369-80.

溶解度数据	In Vitro: H₂O : 100 mg/mL (21.96 mM; Need ultrasonic)配制储备液

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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