Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) 是克拉维酸钾和纤维素的混合物，是一种细菌 β-内酰胺酶 的抑制剂。克拉维酸钾 (Clavulanate potassium) 是克拉维酸 (Clavulanic acid) 的一种形式。克拉维酸钾能抵抗青霉素类和其他抗生素的细菌。克拉维酸钾与阿莫西林结合，可用于研究由细菌引起的不同感染，如鼻窦炎、肺炎、耳部感染、支气管炎、尿路感染、皮肤感染等。

Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Clavulanate potassium is a form of Clavulanic acid. Clavulanate potassium fights bacteria that resistant to penicillins and other antibiotics. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.

Solid

β-lactam

Clavulanate potassium (2 μg/mL) is susceptive to β-lactamase-positive and β-lactamase-negative Bacteroides spp. and Fusobacterium spp. with the combination of amoxicillin (4 μg/mL) and ticarcillin (64 μg/mL).
Clavulanate potassium (16 μg/mL) inhibits B. intermedius , B. bivius , B. disiens , B. oris , B. buccae , B. buccalis and B. loeschei with MIC50 values of 8 μg/mL.
Clavulanate potassium (16 μg/mL) inhibits B. melaninogenicus , B. oralis and F. varium with MIC50 values of 16 μg/mL.
Clavulanate potassium (2 μg/mL) raises amoxicillin susceptibility rates for β-lactamase-positive Bacteroides species and fusobacteria from 41.3 to 90.8% and from 64.2 to 88.7%, respectively. has not independently confirme

Clavulanate potassium (125 mg; 20 d) protects 75% of mice with experimental pneumonitis compared with no survivors in the control group. has not independently confirmed the accuracy of these methods. They are for reference only.

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

[1]. Appelbaum PC, et al. Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers. Antimicrob Agents Chemother. 1990 Aug;34(8):1546-50.
[2]. Beale AS, et al. Comparative activities of amoxycillin, amoxycillin/clavulanic acid and tetracycline against Chlamydia trachomatis in cell culture and in an experimental mouse pneumonitis. J Antimicrob Chemother. 1991 May;2

In Vitro: DMSO : 1 mg/mL (ultrasonic and warming and heat to 80°C)H₂O : < 0.1 mg/mL (insoluble)