rac cis-Moxifloxacin-d4 (hydrochloride)
目录号: PL14643
CAS No. :1217802-65-7
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中文名称
rac cis-Moxifloxacin-d4 (hydrochloride)
中文别名
盐酸莫西沙星 d4 (盐酸盐)
英文名称
rac cis-Moxifloxacin-d4 (hydrochloride)
英文别名
IDIIJJHBXUESQI-RPKOYQESSA-N;rac cis-Moxifloxacin-d4 (hydrochloride);rac cis-Moxifloxacin-d4 Hydrochloride (Major)
Cas No.
1217802-65-7
分子式
C21H25ClFN3O4
分子量
441.92
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
rac cis-Moxifloxacin-d4 (hydrochloride) 是 Moxifloxacin hydrochloride 的氘代物。Moxifloxacin Hydrochloride (BAY 12-8039) 是一种口服有效的 8-甲氧基喹诺酮类抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
生物活性
rac cis-Moxifloxacin-d 4 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2].
体外研究(In Vitro)
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Culley CM, et al. Moxifloxacin: clinical efficacy and safety. Am J Health Syst Pharm. 2001 Mar 1;58(5):379-88.
[3]. Balfour JA, et al. Moxifloxacin: a review of its clinical
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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