Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC 50 of 0.27 μM.
性状
Solid
体外研究(In Vitro)
EC50: 0.27 μM (Wnt/β-catenin). has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Chen DZ, et al. Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/β-catenin signalling pathway agonists. Bioorg Chem. 2019 Mar;84:285-294.
溶解度数据
In Vitro: DMSO : 10 mg/mL (27.51 mM; ultrasonic and warming and heat to 60°C)配制储备液
[1]. Chen DZ, et al. Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/β-catenin signalling pathway agonists. Bioorg Chem. 2019 Mar;84:285-294.