Sulfaclozine sodium

(Synonyms: Sulfachloropyrazine sodium)
目录号: PL12128 纯度: ≥99%
Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物,具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病,禽霍乱和球虫病)的相关研究。
CAS No. :23307-72-4
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中文名称
Sulfaclozine sodium
中文别名
磺胺氯吡嗪鈉;4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
英文名称
Sulfaclozine sodium
英文别名
Benzenesulfonamide,4-amino-N-(6-chloro-2-pyrazinyl)-, sodium salt (1:1);Sodium N-(6-chloropyrazinyl)sulphanilamidate;Sulfaclozine sodium;Sodium sulfaclozine;V2DM5B10CP;Sodium ((4-aminophenyl)sulfonyl)(6-chloropyrazin-2-yl)amide;Sulphachlorpyrazine sodium;sodium;(4-aminophenyl)sulfonyl-(6-chloropyrazin-2-yl)azanide;AK660015;Sulfaclozine sodium, VETRANAL(TM), analytical standard;4-Amino-N-(6-chloropyrazin-2-yl)-N-sodiobenzenesulfonamide;Sodium (4-aminobenzene-1-sulfonyl)(6-chloropyrazin-2-yl)azanid;Sulfachloropyrazine sodium
Cas No.
23307-72-4
分子式
C10H8ClN4NaO2S
分子量
306.70
包装储存
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述
Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物,具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病,禽霍乱和球虫病)的相关研究。
产品详情
Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物,具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病,禽霍乱和球虫病)的相关研究。
生物活性
Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
性状
Solid
IC50 & Target[1][2]
Coccidia
体外研究(In Vitro)
The elimination of Sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Sulfaclozine is weakly adsorbed on the surface of TiO2 at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8 in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of OH and SO4 radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals. has not independently confirmed the accuracy of these methods. They are
体内研究(In Vivo)
Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献
[1]. Sentepe I, et al. Pharmacokinetic of sulfaclozine in broiler chickens. Food Chem Toxicol. 2010 Jan;48(1):448-451.
[2]. Ismail L, et al. Effect of water constituents on the degradation of sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Environ Sci Pollut Res Int. 2018 Jan;25(3):2651-2663.
溶解度数据
In Vitro: H2O : 50 mg/mL (163.03 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)
[1]. Sentepe I, et al. Pharmacokinetic of sulfaclozine in broiler chickens. Food Chem Toxicol. 2010 Jan;48(1):448-451.
[2]. Ismail L, et al. Effect of water constituents on the degradation of sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Environ Sci Pollut Res Int. 2018 Jan;25(3):2651-2663.

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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