Poly-L-lysine hydrochloride|26124-78-7|-陌孚医药/Medlife

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Poly-L-lysine hydrochloride

目录号: PL12214

CAS No. :26124-78-7

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中文名称	Poly-L-lysine hydrochloride
中文别名	聚 L-赖氨酸盐酸盐
英文名称	Poly-L-lysine hydrochloride
英文别名	poly-L-lysine hydrochloride mol. wt.*15,000-30,00;POLY-L-LYSINE HYDROCHLORIDE MW LARGER THAN 20000;L-Lysine hydrochloride;L-Lysine monohydrochloride;lysine hydrochloride;L-Lysine, monohydrochloride;H-Lys-OH.HCl;L-(+)-Lysine Monohydrochloride;(S)-2,6-Diaminohexanoic acid hydrochloride;Lysine HCl;L-lysine HCl;Enisyl;Lyamine;L-Lysine monohydrocholoride;Darvyl;Lysion;(S)-2,6-Diaminohexanoic acid monohydrochloride;L-Lysine, hydrochloride (1:1);L-Gen;JNJ23Q2COM;Lysine, monohydrochloride;(2S)-2,6-diaminohexanoic acid hydrochloride;(S)-2,6-;Poly-L-lysine hydrochloride
Cas No.	26124-78-7
分子式	C₆H₁₅ClN₂O₂
分子量	182.65
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情	Poly-L-lysine hydrochloride 是一种非特异性的细胞附着因子，通过增强细胞膜负离子与培养基表面的静电相互作用，促进细胞对固体基质的粘附。Poly-L-lysine hydrochloride 是一种抗菌肽。Poly-L-lysine hydrochloride 低浓度促进相分离 (Liquid-liquid phase separation，LLPS)，高浓度抑制相分离。
生物活性	Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide..
性状	Solid
体外研究(In Vitro)	Poly-L-lysine is a food-grade antimicrobial peptide that forms complexes with proteins. Such complexes are potential carriers for targeted delivery of agents. Electrostatic potential modelling of EPL was employed to describe the interaction affinity. A three-dimensional phase boundary curve was established which divided the complexation into a nano-scale and phase separation. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Archishman Ghosh, et al. Three archetypical classes of macromolecular regulators of protein liquid-liquid phase separation. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19474-19483. [2]. Liang Guo, et al. pH-induced structural transition during complexation and precipitation of sodium caseinate and ε-Poly-l-lysine. Int J Biol Macromol. 2020 Jul 1;154:644-653.

溶解度数据	In Vitro: H₂O : 50 mg/mL (Need ultrasonic and warming)

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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