JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control.
性状
Solid
体外研究(In Vitro)
In contrast to JAG-1, pretreatment of human pulmonary arterial smooth muscle cells (PASMC) with 50 μM scJag-1 TFA for 30 min has no effect on the transient and plateau components of store-operated Ca entry (SOCE) in comparison to the cells treated with vehicle used to dissolve scJag-1. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
SequenceShortening
RCGPDCFDNYGRYKYCF
参考文献
[1]. Yamamura H, et al. Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol. 2014 May 1;306(9):C871-8.
溶解度数据
In Vitro: H2O : 10 mg/mL (4.50 mM; Need ultrasonic)配制储备液