购物车0
产品总数：61429
| 中文名称 |
α-CGRP, rat TFA
|
|---|---|
| 英文名称 |
α-CGRP, rat TFA
|
| 包装储存 |
Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
|
| 产品详情 |
α-CGRP, rat TFA 是一种神经肽 (降钙素基因相关肽)，主要表达于神经肌肉交界处，是一种有效的血管扩张剂量。α-CGRP, rat TFA 外周给药可使大鼠血压下降、心率升高，并使结肠平滑肌松弛。α-CGRP, rat TFA 可用于心血管、促炎、偏头痛和代谢相关的研究。
|
|---|---|
| 生物活性 |
α-CGRP, rat TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP, rat TFA can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP, rat TFA has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies.
|
| 性状 |
Solid
|
| 体内研究(In Vivo) |
α-CGRP, rat TFA (<0.1 mL; injected above the aorta, single dosage) increases heart rate in a dose dependent fashion. has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model: Male Sprague-Da
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
|
| SequenceShortening |
SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2 (Disulfide bridge:Cys2-Cys7)
|
| 参考文献 |
[1]. Holman JJ, et al. Human alpha- and beta-CGRP and rat alpha-CGRP are coronary vasodilators in the rat. Peptides. 1986 Mar-Apr;7(2):231-5.[2]. Arulmani U, et al. Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats. Basic Clin Pharmacol Toxicol. 2004 Jun;94(6):291-7.
|
| 溶解度数据 |
In Vitro: H2O : 25 mg/mL (6.38 mM; Need ultrasonic)配制储备液
|
|---|
1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。
2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。
Copyright © 2025 陌孚医药 All rights reserved 未经授权禁止拷贝本站所有资料，如有违反，将追究法律责任。
沪ICP备2023012080号 | 
沪公网安备31011402010657号
扫码关注公众号
产品使用指南
