Phenylpiracetam
目录号: PL04270 纯度: ≥99%
CAS No. :77472-70-9
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中文名称
Phenylpiracetam
中文别名
4-苯基-2-吡咯烷酮-1-乙酰胺;卡非多;4-苯基吡拉西坦;苯基吡拉西坦;卡非多(苯基吡拉西坦)
英文名称
Phenylpiracetam
英文别名
2-(2-Oxo-4-phenylpyrrolidin-1-yl)acetamide;2-(2-Oxo-4-phenyl-pyrrolidin-1-yl)acetamide;Phenylpiracetam;2-oxo-4-phenyl-1-Pyrrolidineacetamide;4-Phenyl-2-pyrrolidone-1-acetamide;4-Phenylpiracetam;Carphedon;Carphedone;Fonturacetam;Karfedon;1-Pyrrolidineacetamide, 2-oxo-4-phenyl-;(2-Oxo-4-phenylpyrrolidin-1-yl)acetamide;2-(2-Oxo-4-phenyl-pyrrolidin-1-yl)-acetamide;Fonturacetam [INN];phenypiracetam;Carphedo;Oprea1_208829;Oprea1_429090;MLS000113218
Cas No.
77472-70-9
分子式
C12H14N2O2
分子量
218.25
包装储存
Powder -20°C 3 years;4°C 2 years
产品详情
Phenylpiracetam(Phenotropyl; Phenotropil)是piracetam的苯基衍生物,活性较piracetam高30到60倍。
生物活性
Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. It is used as a stimulant nootropic drug that can be up to 30-60 times more potent than piracetam. IC50 Value: Target: AMPA receptor allosteric modulator in vitro: N/A in vivo: In the open-field test, a significant increase in locomotor activity was observed after a single administration of R-phenotropil at doses of 10 and 50 mg/kg and S-phenotropil at a dose of 50 mg/kg. In the forced swim test, R-phenotropil induced an antidepressant effect at doses of 100 and 50 mg/kg, and S-phenotropil was active at a dose of 100 mg/kg. R-phenotropil significantly enhanced memory function in a passive avoidance response test at a dose of 1 mg/kg; the S-enantiomer did not show any activity in this test [1].
性状
Solid
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Zvejniece L, et al. Investigation into stereoselective pharmacological activity of phenotropil. Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):407-12.
溶解度数据
In Vitro: DMSO : ≥ 100 mg/mL (458.19 mM)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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