Temafloxacin|108319-06-8|-陌孚医药/Medlife

您当前的位置：

Temafloxacin

目录号: PL12100 纯度: ≥99%

CAS No. :108319-06-8

商品编号	规格	价格	会员价
PL12100-5mg	5mg	¥2065.00	请登录
PL12100-10mg	10mg	¥3377.50	请登录
PL12100-25mg	25mg	¥5617.50	请登录
PL12100-50mg	50mg	询价	询价
PL12100-100mg	100mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Temafloxacin
中文别名	替马沙星;乙酸-2-乙基己酯;1-(2,4-二氟苯基)-6-氟-1,4-二氢-7-(3-甲基-1-哌嗪基)-4-氧-3-喹啉羧酸
英文名称	Temafloxacin
英文别名	Temafloxacin;3-Quinolinecarboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-;()-Temafloxacin;1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-Quinolinecarboxylic acid;1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;Temafloxacin HCl;[14C]-Temafloxacin;1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-7-(3-methyl-1-piperazinyl)-quinoline-3-carboxylic acid;1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid;1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid;Omniflox;Temafloxa;Temafloxacina;Temafloxacina [Spanish];Temafloxacine;Temafloxacinum;Temafloxacinum [Latin];Teflox;A-63004;A-62254;AKOS 92085;6-Fluoro-1-(2,4-difluorophenyl)-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid;1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl) -4-oxo-3-quinoline-carboxylic acid;1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quino line-3-carboxylic acid hydrochloride
Cas No.	108319-06-8
分子式	C₂₁H₁₈F₃N₃O₃
分子量	417.39
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情	Temafloxacin (TMFX) 是一种口服有效的喹诺酮类广谱抗菌剂。Temafloxacin 对下呼吸道和泌尿生殖道感染具有较好的耐受性。
生物活性	Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections.
性状	Solid
IC50 & Target[1][2]	Quinolone
体外研究(In Vitro)	Temafloxacin (0-64 μg/mL; 18-24 h) shows good antibacterial activity for gram-positive/negative bacteria, with MIC ranges of <0.004-0.5, 0.5-2 and 0.06-0.25 μg/mL for E. coli , P. aeruginosa , and S. aureus , respectively. has not independently confirmed the accuracy of these methods. They are for reference only.Cell Viability Assay-tbl">
体内研究(In Vivo)	Temafloxacin (6.25, 25, 100 mg/kg; p.o.; single) shows good inhibitory activity to murine pyelonephritis. Temafloxacin hydrochloride (100 mg/kg; p.o. or s.c.; single) shows rapid gastrointestinal absorption, and has excellent tissue and body fluid penetration and concentration (except for central nervous system (CNS)). has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Hardy DJ, et al. Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones. Antimicrob Agents Chemother. 1987 Nov;31(11):1768-74. [2]. Pankey GA. Temafloxacin: an overview. Am J Med. 1991 Dec 30;91(6A):166S-172S.

溶解度数据	In Vitro: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)In Vivo:

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation