Sfllrnpndkyepf|137339-65-2|(SFLLRNPNDKYEPF)-陌孚医药/Medlife

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Sfllrnpndkyepf (Synonyms: SFLLRNPNDKYEPF)

目录号: PL11874 纯度: ≥97%

CAS No. :137339-65-2

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PL11874-50mg	50mg	询价	询价
PL11874-100mg	100mg	询价	询价

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中文名称	Sfllrnpndkyepf
中文别名	凝血酶受体兴奋剂;碘酸锶
英文名称	Sfllrnpndkyepf
英文别名	L-Phenylalanine,L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparaginyl-L-prolyl-L-asparaginyl-L-a-aspartyl-L-lysyl-L-tyrosyl-L-a-glutamyl-L-prolyl-;Thrombin Receptor Agonist;L-Phenylalanine,L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparaginyl-L-prolyl-L-as...;SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE;Thrombin Receptor Agonist Peptide;TRAP-14;TRAP-14, Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human);Thrombin Receptor Activator;Thrombin Receptor Activator Peptide;TRAP;SFLLRNPNDKYEPF
Cas No.	137339-65-2
分子式	C₈₁H₁₁₈N₂₀O₂₃
分子量	1739.92
包装储存	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year

产品详情	Sfllrnpndkyepf 是人工合成的 thrombin 受体激动剂肽段。
生物活性	Sfllrnpndkyepf is a synthetic thrombin receptor agonist peptide.
性状	Solid
体外研究(In Vitro)	Thrombin cleaves its receptor at arginine-41, resulting in the generation of a new receptor NH2-terminus with the sequence Sfllrnpndkyepf. This peptide (TRP-14) may signal a variety of thrombins responses. Sfllrnpndkyepf, representing the 14 amino acids starting with Ser-42 of the human thrombin receptor, was found to mimic the effect of thrombin on platelets. Cleavage of the human platelet thrombin receptor by thrombin exposes a new N-terminal which acts as a putative tethered ligand. Sfllrnpndkyepf, corresponding to the new N-terminal region, activates and induces platelet aggregation and serotonin secretion. Sfllrnpndkyepf is the minimal peptide length which retains full activity in inducing [C]serotonin secretion. TRAP induces rapid morphological changes in HUVECs, with marked increase in the release of prostacyclin, endothelin, platelet activating factor, tissue type plas
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
参考文献	[1]. Sugama Y, et al. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circ Res. 1992 Oct;71(4):1015-9. [2]. Sabo T, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188(2):604-10.

溶解度数据	In Vitro: DMSO : 100 mg/mL (57.47 mM; Need ultrasonic)H₂O : ≥ 50 mg/mL (28.74 mM)

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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