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Sultopride hydrochloride

(Synonyms: 盐酸舒必利; LIN-1418 hydrochloride)

目录号: PL09222 纯度: ≥99%

Sultopride hydrochloride (LIN-1418 hydrochloride) 是多巴胺 D2 受体的选择性拮抗剂。

CAS No. :23694-17-9

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中文名称	Sultopride hydrochloride
中文别名	盐酸舒托必利;N-[(1-乙基-2-吡咯烷基)甲基]-5-(乙基磺酰基)-2-甲氧基苯甲酰胺盐酸盐;舒托必利盐酸盐;盐酸舒妥必利;N-[(1-乙基-2-吡咯烷基)甲基]-5-(乙基磺酰)-2-甲氧基苯甲酰胺盐酸盐
英文名称	Sultopride hydrochloride
英文别名	N-((1-Ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride;Sultopride Hydrochloride;SULTOPRIDE.HCL;N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulphonyl)-2-methoxybenzamide hydrochloride;Sultopride hydrochloride
Cas No.	23694-17-9
分子式	C₁₇H₂₆N₂O₄S^.HCl
分子量	390.93
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情	Sultopride hydrochloride (LIN-1418 hydrochloride) 是多巴胺 D2 受体的选择性拮抗剂。
生物活性	Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.
性状	Solid
IC50 & Target[1][2]	Dopamine D2 receptor
体内研究(In Vivo)	Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05). has not independently confirmed the accuracy of these methods. They are for reference o
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9.

溶解度数据	In Vitro: DMSO : 50 mg/mL (127.90 mM; Need ultrasonic)H₂O : 50 mg/mL (127.90 mM; Need ultrasonic)配制储备液

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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