IL-17A modulator-2 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 27. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC 50 of 8.3. IL-17A modulator-2 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders.
性状
Solid
IC50 & Target[1][2]
IL-17A 8.3 (pIC50)
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献
[1]. Barrie Phillip MARTIN, et al. Preparation of amino acid amides as IL-17A modulators. WO2021239743 A1.
溶解度数据
In Vitro: DMSO : 100 mg/mL (173.12 mM; Need ultrasonic)配制储备液