(1R-cis)-Milnacipran-d10 Hydrochloride;rac-Milnacipran-d10 Hydrochloride;(1R,2S)-2-(aminomethyl)-N,N-bis(1,1,2,2,2-pentadeuterioethyl)-1-phenylcyclopropane-1-carboxamide:hydrochloride;[2H10]- (±)-Milnacipran Hydrochloride;Milnacipran hydrochloride salt;D-Milnacipran D10 hydrochlorideQ: What is
D-Milnacipran D10 hydrochloride Q: What is the CAS Number of
D-Milnacipran D10 hydrochloride Q: What is the storage condition of
D-Milnacipran D10 hydrochloride Q: What are the applications of
D-Milnacipran D10 hydrochloride;Levomilnacipran-d10 Hydrochloride;Milnacipran-d10 (hydrochloride)
Cas No.
1217774-40-7
分子式
C15H23ClN2O
分子量
282.81
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
Milnacipran-d 10 (hydrochloride) is the deuterium labeled Milnacipran hydrochloride. Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia[1][2].
体外研究(In Vitro)
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.[2]. Moret C, et al. Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. Neuropharmacology. 1985 Dec;24(12):1211-9.