Thymalfasin|62304-98-7|(胸腺法新; Thymosin α1)-陌孚医药/Medlife

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Thymalfasin (Synonyms: 胸腺法新; Thymosin α1)

目录号: PL05755 纯度: ≥99%

CAS No. :62304-98-7

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PL05755-50mg	50mg	询价	询价
PL05755-100mg	100mg	询价	询价

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中文名称	Thymalfasin
中文别名	胸腺肽 alpha 1;胸腺 28 肽;胸腺肽(小牛);醋酸胸腺肽α1;胸腺阿尔法一;胸腺肽A-1;胸腺肽Α1(THYMOSINΑ1);▲胸腺法新;胸腺法新;胸腺素α1(胸腺素a-1) 胸腺肽α1;胸腺肽;胸腺肽alpha 1, 胸腺28 肽;胸腺肽α1;胸腺肽α1 Thymosin α1 Acetate;胸腺肽α1 Thymosinα1Acetate;胸腺五肽;醋酸胸腺肽 Alpha1;胸腺肽 α1;胸腺28肽杂质;醋酸胸腺α1
英文名称	Thymalfasin
英文别名	Thymosin alpha 1;ACETYL-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN;AC-SDAAVDTSSEITTKDLKEKKEVVEEAEN;AC-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN;AC-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN-OH;THYMOSIN A1;THYMOSIN A1 BOVINE;THYMOSIN ALPHA1 BOVINE;Thymosin alpha-1;Thymosin α₁;Thymosin α1 Acetate;Thymosin α1 bovine;Thymosin-1;Thymosinα1;Thymosin ?1;Thymosin Alpha1 Acetate;THYMOSIN APHA 1;Thymosina1Acetate;ZADAXIN;Thymosina1 (ox);L-Asparagine,N-acetyl-L-seryl-L-a-aspartyl-L-alanyl-L-alanyl-L-valyl-L-a-aspartyl-L-threonyl-L-seryl-L-seryl-L-a-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-a-aspartyl-L-leucyl-L-lysyl-L-a-glutamyl-L-lysyl-L-lysyl-L-a-glutamyl-L-valyl-L-valyl-L-a-glutamyl-L-a-glutamyl-L-alanyl-L-a-glutamyl-;Thymosina1 (human);thymosin а1;N-Acetyl-L-seryl-L-alpha-aspartyl-L-alanyl-L-alanyl-L-valyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-valyl-L-valyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-asparagine;Thymosin alpha impurity
Cas No.	62304-98-7
分子式	C₁₂₉H₂₁₅N₃₃O₅₅
分子量	3108.30
包装储存	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year

产品详情

Thymalfasin (thymosin-alpha 1) 是一个免疫调节化合物，能够提高 Thl 的免疫应答。

生物活性

Thymalfasin is an immunomodulating agent able to enhance the Thl immune response.

性状

Solid

体外研究(In Vitro)

Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects. has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year

ClinicalTrial

SequenceShortening

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN

Sequence

N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn

参考文献

[1]. Lao X et al. A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. Apoptosis. 2015 Oct;20(10):1307-20.
[2]. Sjogren MH et al. Thymalfasin: an immune system enhancer for the treatment of liver disease. J Gastroenterol Hepatol. 2004 Dec;19(12):S69-72.

溶解度数据	In Vitro: H₂O : 0.3 mg/mL (0.10 mM; Need ultrasonic and warming)In Vivo:

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产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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