[2H4]-Risedronic acid;Risedronic Acid-d4 (Major);IIDJRNMFWXDHID-RZIJKAHPSA-N;Risedronic acid D4Q: What is
Risedronic acid D4 Q: What is the CAS Number of
Risedronic acid D4 Q: What is the storage condition of
Risedronic acid D4 Q: What are the applications of
Risedronic acid D4
Cas No.
1035438-80-2
分子式
C7H11NO7P2
分子量
283.11
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
Risedronic Acid-d 4 is the deuterium labeled Risedronic acid. Risedronic acid (Risedronate) is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption[1][2].
体外研究(In Vitro)
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.[2]. Giljevic Z, et al. Treatment of osteoporosis by risedronate-- speed, efficacy and safety. Reumatizam. 2006;53(2):66-71.[3]. Jordao FM, et al. In vitro and in vivo antiplasmo