Dibenzoyl Thiamine

目录号: PL12579 纯度: ≥99%
Dibenzoyl Thiamine (Bentiamine) 是硫胺素的衍生物。在体内被快速吸收到并转化成硫胺素。
CAS No. :299-88-7
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中文名称
Dibenzoyl Thiamine
中文别名
二苯甲酰硫胺素;Dibenzoyl Thiamine 二苯甲酰硫胺素;苯甲硫胺;联苯甲酰硫胺;二苯甲酰硫胺;二苯甲酰硫胺素盐酸盐
英文名称
Dibenzoyl Thiamine
英文别名
Benzenecarbothioicacid,S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(benzoyloxy)ethyl]-1-propen-1-yl]ester;Dibenzoyl Thiamine;[(Z)-4-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-3-benzoylsulfanylpent-3-enyl] benzoate;Bentiamine;Benzenecarbothioicacid,S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(benzoy...;Bentiamina [INN-Spanish];Bentiamine [INN];Bentiaminum [INN-Latin];Dibenzoylthiamin;N-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-N-(4-benzoyloxy-2-benzoylsulfanyl-1-methyl-but-1-enyl)-formamide;O,S-Bis(benzoyl)thiamine disulfide;O,S-Dibenzoyl-thiamin;O,S-Dibenzoylthiamine;Dibenzoylthiamine;O,S-Dibenzoyl thiamine;8PUY50JWLU;Bentiamine (INN);4-(N-((4-Amino-2-methylpyrimidin-5-yl)methyl)formamido)-3-(benzoylthio)pent-3-en-1-yl benzoate;Bentiaminum;Bentiamina;Benzoic acid, thio-, S-ester with N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydroxy-2-mercapto-1-meth
Cas No.
299-88-7
分子式
C26H26N4O4S
分子量
490.57
包装储存
Powder -20°C 3 years;4°C 2 years
详情描述
Dibenzoyl Thiamine (Bentiamine) 是硫胺素的衍生物。在体内被快速吸收到并转化成硫胺素。
产品详情
Dibenzoyl Thiamine (Bentiamine) 是硫胺素的衍生物。在体内被快速吸收到并转化成硫胺素。
生物活性
Dibenzoyl Thiamine (Bentiamine), a derivative of thiamine, is rapidly absorbed into the body and converted to thiamine.
性状
Solid
体外研究(In Vitro)
Dibenzoyl Thiamine is a thiol-type thiamine composed of thiamine and benzoic acid. It is not decomposed by aneurinase (thiamine-decomposing enzyme), making it more suitable for food processing than thiamine hydrochloride. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
A chronic toxicity study in male Wistar rats for 6 months at dietary levels of up to 1000 ppm, shows Dibenzoyl Thiamine to be without specific toxic effects. A teratogenicity study in rats show Dibenzoyl Thiamine to be without embryotoxic or teratogenic effects. Tests for mutagenicity in bacterial systems, in the dominant lethal assay and in an in vivo cytogenetics test show Dibenzoyl Thiamine to be without mutagenic. Dibenzoyl Thiamine is metabolised to Vitamin Br and benzoic acid, and the benzoic acid moiety is almost quantitatively excreted in the urine, as hippuric acid. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Heywood R, et al. Tumorigenic and toxic effect of O,S-dibenzoyl thiamine hydrochloride in prolonged dietaryadministration to rats. Toxicol Lett. 1985 Jul;26(1):53-8.
溶解度数据
In Vitro: DMSO : 50 mg/mL (101.92 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)
[1]. Heywood R, et al. Tumorigenic and toxic effect of O,S-dibenzoyl thiamine hydrochloride in prolonged dietaryadministration to rats. Toxicol Lett. 1985 Jul;26(1):53-8.

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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