HKSOX-1m (5/6-mixture) is a O 2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O 2 over a broad range of pH, strong oxidants, and abundant reductants found in cells.
体外研究(In Vitro)
HKSOX-1m (5/6-mixture) (10 μM) 能够灵敏地在非常低的激光功率输出条件下,捕获分化的人 THP-1 细胞的基础信号,和受 Antimycin A (1 μM) 刺激的线粒体 O2 的信号 (蔡司 LSM 510 Meta 的 514 nm 激发波长的强度为 1%)。 has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jun Jacob Hu, et al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc . 2015 Jun 3;137(21):6837-43.
溶解度数据
In Vitro: DMSO : 55 mg/mL (47.02 mM; Need ultrasonic)配制储备液