Fluphenazine decanoate 是一种多巴胺 D₂ 受体抑制剂和吩噻嗪类精神安定剂 (neuroleptic)。Fluphenazine decanoate可用于精神分裂症的研究。

Fluphenazine decanoate is a dopamine D 2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research.

Oil

D2 Receptor

Fluphenazine decanoate shows activity against T. gondii in human fibroblast cell cultures with an IC50 value of 1.7 mM.
has not independently confirmed the accuracy of these methods. They are for reference only.

Fluphenazine decanoate (0.22 mg/kg and followed by 0.33 mg/kg; i.m.; 8 times every 3 weeks), as an antipsychotic, increases sensitivity to dopamine on monkey model following extended treatment.
Fluphenazine decanoate (25 mg/kg; i.m.; 6 times every 3 weeks; 24 weeks) induces mouth movements in the rat, serves as a pharmacological model of human tardive dyskinesia.
Fluphenazine decanoate (1, 2, 3 mg/kg/d; s.c.; 60 d) shows antifertility effects and induces hyperprolactinemia concomitant with gonadotropin suppression in adult male rat.
has not independently confirmed the accuracy of these methods. They are for reference only.

Room temperature in continental US; may vary elsewhere.

Pure form -20°C 3 years；4°C 2 years

[1]. Goodwin DG, et al. Evaluation of five antischizophrenic agents against Toxoplasma gondii in human cell cultures. J Parasitol. 2011 Feb;97(1):148-51.
[2]. Lifshitz K, et al. Effects of dopamine agonists on Cebus apella monkeys with previous long-term exposure to fluphenazine. Biol Psychiatry. 1997 Mar 15;41(6):657-67.

In Vitro: DMSO : 125 mg/mL (211.23 mM; Need ultrasonic)Ethanol : 50 mg/mL (84.49 mM; Need ultrasonic)配制储备液