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Dipivefrin hydrochloride

(Synonyms: Dipivefrine hydrochloride)

目录号: PL09091 纯度: ≥99%

Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体药物，通过角膜中的酯酶水解为其活性化合物肾上腺素。

CAS No. :64019-93-8

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中文名称	Dipivefrin hydrochloride
中文别名	盐酸地匹福林;4-(1-羟基-2-(甲基氨基)乙基)-1,2-苯二醇二特戊酸酯盐酸盐;盐酸地匹福林 EP标准品;盐酸地匹福林 USP标准品;盐酸地匹福林标准品
英文名称	Dipivefrin hydrochloride
英文别名	Dipivefrin hydrochloride;[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate,hydrochloride;Dipivefrine Hydrochloride;(1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochloride;AKPro;Dipivalyl epinephrine hydrochloride;Dipivefrin HCL;EINECS 264-609-5;4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochloride;[2-(2,2-Dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate hydrochloride
Cas No.	64019-93-8
分子式	C₁₉H₂₉NO₅^.HCl
分子量	387.90
包装储存	-20°C, stored under nitrogen, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
详情描述	Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体药物，通过角膜中的酯酶水解为其活性化合物肾上腺素。

产品详情	Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体药物，通过角膜中的酯酶水解为其活性化合物肾上腺素。
生物活性	Dipivefrin hydrochloride (Dipivefrine hydrochloride) is an antiglaucoma prodrug that is hydrolyzed to the active compound, epinephrine, by esterases in the cornea.
性状	Solid
体内研究(In Vivo)	Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms. has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-20°C, stored under nitrogen, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
参考文献	[1]. Edgar DF, et al. Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and LogMAR acuity. Graefes Arch Clin Exp Ophthalmol. 1999 Feb;237(2):117-24. [2]. Anderson JA, et al. Effects of echothiophate on enzymatic hydrolysis of dipivefrin. Arch Ophthalmol. 1984 Jun;102(6):913-6. [3]. Introin

溶解度数据	In Vitro: DMSO : 250 mg/mL (644.50 mM; Need ultrasonic)配制储备液

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[1]. Edgar DF, et al. Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and LogMAR acuity. Graefes Arch Clin Exp Ophthalmol. 1999 Feb;237(2):117-24.
[2]. Anderson JA, et al. Effects of echothiophate on enzymatic hydrolysis of dipivefrin. Arch Ophthalmol. 1984 Jun;102(6):913-6.
[3]. Introin

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Dipivefrin hydrochloride

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