Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research .
体外研究(In Vitro)
在全血中,Enlimomab 以补体依赖的方式激活静息中性粒细胞。 has not independently confirmed the accuracy of these methods. They are for reference only.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7. [2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8.
[1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7. [2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8.