Vecuronium bromide|50700-72-6|(维库溴铵; ORG NC 45)-陌孚医药/Medlife

您当前的位置：

Vecuronium bromide (Synonyms: 维库溴铵; ORG NC 45)

目录号: PL07651 纯度: ≥98.0%

CAS No. :50700-72-6

商品编号	规格	价格	会员价
PL07651-50mg	50mg	¥1285.00	请登录
PL07651-100mg	100mg	¥1928.00	请登录
PL07651-200mg	200mg	询价	询价
PL07651-500mg	500mg	询价	询价
PL07651-10mM*1mLinDMSO	10mM*1mLinDMSO	¥1414.00	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Vecuronium bromide
中文别名	维库溴铵;溴化凡寇罗宁;溴化万科罗宁;维库罗宁;诺库隆;维库溴铵水合物;Vecuronium Bromide Hydrate 维库溴铵水合物;维库峰鉴别 EP标准品;维库溴铵 EP标准品;维库溴铵 USP标准品;维库溴铵技术转让;维库溴铵(肌松药);维库溴铵,M.O.H.Standard, In-house Standard;1-[(2β,3α,5α,16β,17β)-3,17-双(乙酰氧基)-2-(1-哌啶基)雄甾-16-基]-1-甲基溴化哌啶水合物
英文名称	Vecuronium bromide
英文别名	Vecuronium Bromide;Norcuron;(+)-1-(3,17-Diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium bromide;Vecuronium Bromide Hydrate;Vecuronium (bromide);VECURONIUM BROMIDE, EP;1-(3,17-Diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium bromide;1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide;1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide Hydrate;ORG NC 45;Vecuronium bromide
Cas No.	50700-72-6
分子式	C₃₄H₅₇BrN₂O₄
分子量	637.74
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情

Vecuronium (ORG NC 45) bromide 是一种非去极化神经肌肉阻滞剂，也可作为烟碱乙酰胆碱受体 (nAChR) 抑制剂，肌肉松弛剂，可用于手术前麻醉。

生物活性

Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia.

性状

Solid

体外研究(In Vitro)

Vecuronium bromide (0-100 μM, 15 min) inhibits [H] norepinephrine (NE) uptake to 65% at 100 μM in adrenal medullary cells.
Vecuronium bromide (0-15 μM,72 hours) inhibits cancer cell proliferation and migration in a concentration-dependent manner.
Vecuronium bromide (0-15 μM,72 hours) can significantly reduce cell viability by combining with cisplatin.
has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

Vecuronium bromide (Intravenous injection, 0-5 μM, every 30 min, 2 hours) attenuates the response of carotid sinus nerve activity (CSNA) to hypoxia in a dose-dependent manner and inhibits the neural response of the carotid body to acetylcholine (ACh) in Wister rats.
has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

ClinicalTrial

参考文献

[1]. K Uryu, et al. Inhibition by neuromuscular blocking drugs of norepinephrine transporter in cultured bovine adrenal medullary cells. Anesth Analg. 2000 Sep;91(3):546-51.
[2]. Iddrisu BabaYabasin, et al. Anticancer effects of vecuronium bromide and cisatracurium besylate on lung cancer cells (A549), in vitro. Biomedicine & Aging Pathology,Volume 4, Issue 4,

溶解度数据	In Vitro: H₂O : ≥ 100 mg/mL (156.81 mM)DMSO : ≥ 46 mg/mL (72.13 mM)

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation