Tris(4-aminophenyl)methane (Synonyms: Leucopararosaniline)
目录号: PL05599 纯度: ≥98%
CAS No. :548-61-8
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中文名称
Tris(4-aminophenyl)methane
中文别名
4,4',4"-三氨基三苯甲烷;三(4-氨基苯基)甲烷;4,4',4"三氨基三苯甲烷;4,4'',4"-三氨基三苯甲烷;4,4,4-三氨基三苯甲烷;4,4’,4"-三氨基三苯甲烷;4,4’,4’-三氨基三苯甲烷;4,4`,4```-三氨基三苯甲烷;副品红隐色基;三(4-苯胺基)甲烷;4,4',4''-甲烷三基三苯胺
英文名称
Tris(4-aminophenyl)methane
英文别名
4,4',4''-Methanetriyltrianiline;Tris(4-aminophenyl)methane;4-[bis(4-aminophenyl)methyl]aniline;Tris(4-aminophenyl)-methane;4,4',4"-Methanetriyltrianiline;Leucopararosaniline;Leucoparafuchsin;Leucoparafuchsine;Triaminotriphenylmethane;4,4',4''-Methylidynetrianiline;p,p',p''-Triaminotriphenylmethane;4,4',4''-Triaminotriphenylmethane;Tris-4-aminofenylmethan [Czech];Aniline, 4,4',4''-methylidynetri-;4,4',4''-Methylidynetrisbenzeneamine;Methane, tris(4-aminophenyl)-;Benzeneamine, 4,4',4''-methylidynetris- (9CI);C
Cas No.
548-61-8
分子式
C19H19N3
分子量
289.37
包装储存
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
产品详情
Tris(4-aminophenyl)methane 是一种三苯甲烷类染料。Tris(4-aminophenyl)methane 是一种稍弱的 HCV 解旋酶 (HCV helicase) 抑制剂。
生物活性
Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
性状
Solid
IC50 & Target[1][2]
HCV helicase
体外研究(In Vitro)
Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM). To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献
[1]. Chen CS, et al. Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virushelicase. J Med Chem. 2009 May 14;52(9):2716-23.
溶解度数据
In Vitro: DMSO : 50 mg/mL (172.79 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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